Results 101 to 110 of about 22,299 (230)

GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
GLP‐1R signaling integrates metabolic state with neural circuits controlling reward, mood, and memory, acting as a metabolic‐cognitive interface. In reward pathways, it suppresses hedonic feeding and drug seeking; in affective circuits, sustained signaling promotes anxiolytic and antidepressant effects; and in the hippocampus, it enhances synaptic ...
Serena X. Gao, Léa Décarie‐Spain, Cindy Gu, Giulia Mazzini, Scott E. Kanoski, Tito Borner   +5 more
wiley   +1 more source

Sociodemographic and clinical profiles of individuals with opioid dependence syndrome presenting to a tertiary care center in Assam: A retrospective review

Indian Journal of Psychiatry
Background: Opioid dependence is a critical public health issue in Northeast India, with limited data available on the affected population. Aim: This study examines the sociodemographic and clinical profiles of opioid-dependent individuals in Assam ...
Pranjal J. Chakravarty, Tathagata Mahintamani, Diptadhi Mukherjee, Partha P. Daimary, Hemanta Dutta   +4 more
doaj   +1 more source

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu, Xinyue Zhou, Ruotong Meng, Yanxi Chen, You Chen, Blake Highet, Maurice Curtis, Bernhard Hirt, Shunying Yu, Jin Zhou, Linya You   +10 more
wiley   +1 more source

Substance and Behavioural Addictions Among Evacuees: Findings From Israeli Swords of Iron War

Stress and Health, Volume 42, Issue 2, April 2026.
ABSTRACT War‐related evacuation is a stressful event that may cause mental health problems, which, in turn, might lead to increases in substance and behavioural addictions. We used data collected online during the Swords of Iron to examine associations between being evacuated during the war, mental health, problematic substance use, and behavioural ...
Gabriella Rubin, Uri Lifshin, Vera Skvirsky, Yoav Ankri, Dvora Shmulewitz, Maor Levitin, Merav Vider, Shaul Lev‐Ran, Ariel Kor, Mario Mikulincer   +9 more
wiley   +1 more source

Contingency management interventions for substance use and addictive behaviours: Review of the United Kingdom evidence base

Addiction, Volume 121, Issue 4, Page 729-746, April 2026.
Abstract Background and aims Substance use and other addictive behaviours including gambling remain major public health concerns in the UK. Despite the effectiveness of substance use treatment approaches, treatment adherence and success rates remain low.
Carol‐Ann Getty, Tricia McQuarrie, Eileen Brobbin   +2 more
wiley   +1 more source

Drug use among people in prison: A global review of epidemiology, harms and interventions

Addiction, Volume 121, Issue 4, Page 749-764, April 2026.
Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley   +1 more source

Walking With SAGE Clan Patrol: Practicing Empathy in the Indigenous Urban Landscape

City &Society, Volume 38, Issue 1, April 2026.
ABSTRACT This article examines the work of a Blackfoot‐led, volunteer‐based outreach organization that patrols the urban core of Lethbridge, Alberta, Canada, providing support and connection to vulnerable community members. While settler colonialism maintains exclusionary racialized geographies which locate cities as spaces of “Whiteness” and reserves ...
Amy Cran, Patrick C. Wilson, Mark Brave Rock   +2 more
wiley   +1 more source

Stress reactivity in heroin dependence

, 2015
Background: Heroin dependence is a chronic relapsing disorder characterized by a compulsion to seek and use heroin despite the negative consequences. In addition to the diagnostic criteria, heroin dependence is associated with an altered function of the hypothalamic-pituitary-adrenal (HPA) axis and with affective disturbances and other mental disorders.
openaire   +3 more sources

Effectiveness of School‐Based Resilience Interventions on Adolescent Tobacco, Alcohol, and Illicit Substance Use: A Meta‐Analysis

Journal of School Health, Volume 96, Issue 4, April 2026.
ABSTRACT BackgroundResilience is a key protective factor in mitigating substance use behaviors in adolescence, but the effectiveness of school‐based resilience interventions remains unclear. MethodsRandomized and quasi‐experimental studies evaluating school‐based resilience interventions for tobacco, alcohol, or illicit substance use among students ...
Jisoo Chae, Hyekyeong Kim
wiley   +1 more source

Study of the Transition from Non-Injection to Injection in Heroin Users

پزشکی بالینی ابن سینا, 2010
Introduction & Objectives: The goal of our study was to elucidate the time and factors influencing the transition from non-injection to injection among male heroin users.
Mosaieb Yarmohammadi Vasel, Fatemeh Ghanadi   +1 more
doaj