Results 111 to 120 of about 24,412 (283)

CORRELATIONS BETWEEN AWARENESS OF ILLNESS (INSIGHT) AND HISTORY OF ADDICTION IN HEROIN-ADDICTED PATIENTS

open access: yesFrontiers in Psychiatry, 2012
In a group of 1066 heroin addicts, who were seeking treatment for opioid agonist treatment, we looked for differences in historical, demographic and clinical characteristics, between patients with different levels of awareness of illness (insight).
Angelo Giovanni Icro eMaremmani   +15 more
doaj   +1 more source

Trends in new psychoactive substance poisonings in the Netherlands: A 14‐year retrospective analysis (2012–2025)

open access: yesAddiction, EarlyView.
Abstract Background and aims Data on the presence of new psychoactive substances (NPS) mainly originate from drug‐checking, law enforcement and wastewater analysis sources, while data on NPS poisonings are scarce. In Europe, the documented incidence rate of NPS poisonings is highest in the Netherlands.
Johanna J. Nugteren‐van Lonkhuyzen   +5 more
wiley   +1 more source

Inflammatory chemokine eotaxin-1 is correlated with age in heroin dependent patients under methadone maintenance therapy [PDF]

open access: yes, 2018
[[abstract]]BACKGROUND: Degeneration of central neurons and fibers has been observed in postmortem brains of heroin dependent patients. However, there are no biomarkers to predict the severity of neurodegeneration related to heroin dependence.
Kuo, HW;Liu, TH;Tsou, HH;Hsu, YT;Wang, SC;Fang, CP;Liu, CC;Chen, ACH;Liu, YL
core   +1 more source

Validation of the Substance Use Risk Profile Scale (SURPS) With Bulgarian Substance Dependent Individuals

open access: yesFrontiers in Psychology, 2018
Background: The Substance Use Risk Profile Scale (SURPS) is a 23-item self-report questionnaire that assesses four well-validated personality risk factors for substance misuse (Impulsivity, Sensation Seeking, Anxiety Sensitivity, and Hopelessness). While
Elizabeth C. Long   +10 more
doaj   +1 more source

Craving and personal functioning as mediators of extended‐release buprenorphine efficacy: A four‐way decomposition analysis from a randomised trial

open access: yesAddiction, EarlyView.
Abstract Aims To investigate whether the treatment effect of extended‐release buprenorphine (BUP‐XR) on opioid‐free days in opioid use disorder (OUD) is mediated by reductions in opioid craving and improvements in personal functioning. Design and setting Exploratory causal mediation analysis using VanderWeele's four‐way decomposition framework in a 24 ...
John Marsden   +11 more
wiley   +1 more source

Influence of brain-derived neurotrophic factor genetic polymorphisms on the ages of onset for heroin dependence in a Chinese population [PDF]

open access: yes, 2012
Aim: The study aims at evaluating the association between brain-derived neurotrophic factor (BDNF) gene polymorphisms and heroin-dependent patients in the Chinese population.
Gao, Xuan   +7 more
core   +2 more sources

Association of a Common NOS1AP Variant with Attenuation of QTc Prolongation in Men with Heroin Dependence Undergoing Methadone Treatment. [PDF]

open access: yesJ Pers Med, 2022
Chang KC   +9 more
europepmc   +1 more source

Treatment of heroin dependence with ibogaine

open access: yesEuropean Psychiatry, 2016
BackgroundThe use of the hallucinogen ibogaine as an anti-addiction agent has been described in several case reports, dating back to the eighties. The anti-addiction properties of ibogaine have been confirmed in a large body of animal work. Ibogaine has been shown to be effective in reducing withdrawal severity and substance use for a variety of ...
Schellekens, A.F.A.   +4 more
openaire   +2 more sources

Leucine Aminopeptidase from Xanthomonas oryzae pv. oryzae with Esterase Activity Toward Heroin: Biochemical and Catalytic Insights

open access: yesBiomolecules
Heroin is a highly addictive drug that exerts its primary effects through activation of μ-opioid receptors. Its principal active metabolite, 6-monoacetylmorphine (6-MAM), significantly contributes to heroin’s neurological effects and acute toxicity ...
Hualing Li   +10 more
doaj   +1 more source

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