Results 131 to 140 of about 22,299 (230)

Heroin dependents are insulin resistant

open access: yes, 2011
Background. Fasting insulin levels, HOMA-IR and HOMA-%B are precise methods for determining insulin resistance and can be used in assessing the insulin sensitivity in heroin dependents (HD). Heroin dependents are expected to be insulin resistant. To determine the heroin influence on insulin sensitivity in male heroin dependents compared to control ...
Janikevik Ivanovska, Danijela   +3 more
openaire   +1 more source

Context features influence alcohol reward and motivation

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 3, March 2026.
The alcohol intake environment can exert powerful long‐term effects on alcohol motivation and relapse through alcohol‐context associative learning. In this study in mice, we determined that alcohol‐context learning depends upon the specific sensory and spatial features of the context.
Surya Pandey, Courtney A. Miller
wiley   +1 more source

Neural Correlates of Drug-Related Attentional Bias in Heroin Dependence. [PDF]

open access: yesFront Hum Neurosci, 2017
Zhao Q   +6 more
europepmc   +1 more source

Psilocybin and Ibogaine in Cocaine‐Seeking: Extinction Enhancement Without Relapse Prevention

open access: yesAddiction Biology, Volume 31, Issue 3, March 2026.
Using a preclinical model of cocaine self‐administration, we examined the effects of psilocybin and ibogaine on extinction learning and relapse‐like behaviour. Both compounds, administered during the extinction phase, reduced cocaine seeking, indicating facilitation of extinction learning. However, neither treatment prevented cue‐induced reinstatement.
Isis Rita Anzel Koutrouli   +16 more
wiley   +1 more source

The Buprenorphine Paradox: How Buprenorphine Triggers and Resolves Opioid Withdrawal

open access: yesAddiction Biology, Volume 31, Issue 3, March 2026.
Buprenorphine can either precipitate or relieve opioid withdrawal depending on the timing of administration relative to full opioid agonist exposure. The article proposes that buprenorphine promotes mu‐opioid receptor (MOR) externalization and resensitization, creating a temporary signaling gap that explains precipitated withdrawal when full agonists ...
Mehdi Haghdoost   +6 more
wiley   +1 more source

Fentanyl, Methamphetamine and Polysubstance Use Differentially Affect Locomotor Sensitisation and Social Behaviour in Rats: Psychedelic Treatment Reverses Social Deficits

open access: yesAddiction Biology, Volume 31, Issue 3, March 2026.
Polysubstance opioid–stimulant use is increasingly prevalent, yet its behavioral consequences remain poorly understood. We compared single versus combined fentanyl and methamphetamine exposure in male and female rats, assessing locomotor sensitization and sociability during withdrawal.
Leah M. Salinsky   +4 more
wiley   +1 more source

Managing the Complex Intersection Between Substance Use Disorders and Infectious Diseases

open access: yes
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 3, March 2026.
Karissa Chow   +4 more
wiley   +1 more source

Characteristics of methamphetamine‐related deaths in the United Kingdom, 1997–2024

open access: yesAddiction, Volume 121, Issue 3, Page 680-685, March 2026.
Abstract Background and aims People who use methamphetamine have a standardised mortality ratio 6.8 times greater than the general population, with several countries reporting concerning increases in methamphetamine‐related mortality over the past decade.
Emmert Roberts   +2 more
wiley   +1 more source

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