Results 141 to 150 of about 375,473 (301)

Naloxone dosing in the era of synthetic opioids: Applying the Goldilocks principle

Addiction, EarlyView.
Abstract The opioid overdose epidemic remains a critical public health crisis. In recent years, synthetic opioids like fentanyl and nitazenes, have driven a sharp rise in deaths. Naloxone, an opioid receptor antagonist, has been established as a key intervention for reversing opioid overdoses and saving lives.
Mariana Gonzalez Utrilla, Edward Chesney, Joanne Neale, Nicola Metrebian, Nicola Kalk, Arne Kristian Skulberg, Paul Dietze, Martin Smith, John Strang   +8 more
wiley   +1 more source

A Knowledge Graph-based Approach for Exploring the U.S. Opioid Epidemic [PDF]

arXiv, 2019
The United States is in the midst of an opioid epidemic with recent estimates indicating that more than 130 people die every day due to drug overdose. The over-prescription and addiction to opioid painkillers, heroin, and synthetic opioids, has led to a public health crisis and created a huge social and economic burden.
arxiv  

Morbidity and mortality from heroin dependence. 1. Survey of heroin addicts known to home office. [PDF]

, 1968
T. H. Bewley, O. Ben-Arie, I. Pierce James   +2 more
openalex   +1 more source

Craving self‐reports as outcome measures in drug addiction trials: A systematic review of ClinicalTrials.gov

Addiction, EarlyView.
Abstract Background and Aims The subjective experience of drug craving is characterized by an overwhelming urge to consume substances. Due to strong validity and ease of use, self‐report measures are widely employed to assess substance‐related motivational dynamics.
Matin Toulami, Keyvan Ghasemi, Parnian Rafei, Arshiya Sangchooli, Nastaran Nafissi, Arash Khojasteh Zonoozi, Hossein Mohaddes Ardabili, Mohsen Ebrahimi, Tara Rezapour, Hamed Ekhtiari   +9 more
wiley   +1 more source

Morbidity and mortality from heroin dependence. 3. Relation of hepatitis to self-injection techniques. [PDF]

, 1968
T. H. Bewley, O. Ben-Arie, V. Marks
openalex   +1 more source

Stress reactivity in heroin dependence

, 2015
Background: Heroin dependence is a chronic relapsing disorder characterized by a compulsion to seek and use heroin despite the negative consequences. In addition to the diagnostic criteria, heroin dependence is associated with an altered function of the hypothalamic-pituitary-adrenal (HPA) axis and with affective disturbances and other mental disorders.
openaire   +3 more sources

The landscape of ketamine use disorder: Patient experiences and perspectives on current treatment options

Addiction, EarlyView.
Abstract Aims To report the symptoms and aetiology of ketamine use disorder (KUD), gauge the effectiveness of current treatment services and identify strategies to enhance patient access and outcomes. Design Mixed‐methods, cross‐sectional questionnaire. Electronic survey from November 2023 to April 2024.
Rebecca E. Harding, Tamsin Barton, Maeve Niepceron, Ella Harris, Emily Bennett, Emily Gent, Flora Fraser, Celia J. A. Morgan   +7 more
wiley   +1 more source

The importance of vanillylmandelic acid determination in opiate users [PDF]

Journal of Medical Biochemistry, 2009
Although knowledge about the etiology of heroin dependence is rather poor, it is known that the influence of opiates on the opioid, adrenergic and indirectly of GABA on the dopaminergic receptors leads to changes of catecholamine levels in brain ...
Janićević-Ivanovska Danijela, Spasovska-Trajkovska Aneta, Stefanovski Branko, Subeska-Stratrova Slavica, Mečevska-Jovčevska Jasmina   +4 more
doaj  

Prevalence and correlates of alcohol dependence in adult prisoners vary according to Indigenous status

Australian and New Zealand Journal of Public Health, 2012
Objective : To estimate the prevalence and identify independent correlates of alcohol dependence among Indigenous and non‐Indigenous adult prisoners in Queensland.
Stuart A. Kinner, Paul M. Dietze, Maelenn Gouillou, Rosa Alati   +3 more
doaj   +1 more source

Cocaine and heroin dependence compared in poly-drug abusers. [PDF]

, 1988
Deborah S. Hasin, Bridget F. Grant, Jane Endicott, Thomas C. Harford   +3 more
openalex   +1 more source