Results 171 to 180 of about 1,704,994 (242)
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Clinical Pharmacology & Therapeutics, 1968
Naloxone is a potent and rapidly acting narcotic antagonist, with a duration of action which is shorter (3 to 4 hours) than that of heroin. In a clinical trial of naloxone in the treatment of heroin dependence, a daily oral dose of 100 mg. at 8 A.M. and 7 P.M. effectively blockaded 20 mg.
M, Fink +6 more
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Naloxone is a potent and rapidly acting narcotic antagonist, with a duration of action which is shorter (3 to 4 hours) than that of heroin. In a clinical trial of naloxone in the treatment of heroin dependence, a daily oral dose of 100 mg. at 8 A.M. and 7 P.M. effectively blockaded 20 mg.
M, Fink +6 more
openaire +2 more sources
Journal of Affective Disorders, 2019
BACKGROUND Although individuals who experience childhood emotional maltreatment (CEM) are more likely to use maladaptive emotion regulation strategies, resulting in vulnerability to depression, no research has examined whether emotion dysregulation may ...
V. Khosravani +4 more
semanticscholar +1 more source
BACKGROUND Although individuals who experience childhood emotional maltreatment (CEM) are more likely to use maladaptive emotion regulation strategies, resulting in vulnerability to depression, no research has examined whether emotion dysregulation may ...
V. Khosravani +4 more
semanticscholar +1 more source
Heroin maintenance for chronic heroin dependents
2003Dependent heroin users are characterised by the persistence of use in spite of the difficulties they experience with health, law, social achievements and personal relationships. The present review will consider maintenance treatment in which the patients enter programs of pharmacological administration tailored to achieve patient stabilisation.
M, Ferri, M, Davoli, C A, Perucci
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The long-term impact of post traumatic stress disorder on recovery from heroin dependence.
Journal of Substance Abuse Treatment, 2018The high prevalence of post traumatic stress disorder (PTSD) among people with heroin dependence and its impact on short term outcomes has been well established. The impact of PTSD on long-term recovery is, however, unknown.
K. Mills +5 more
semanticscholar +1 more source
Acute effects of heroin on emotions in heroin‐dependent patients
The American Journal on Addictions, 2013BackgroundEuphoria has been described in heroin‐dependent individuals after heroin administration. However, affective disturbances and disorders are common in heroin dependence. The present study examined the acute effects of heroin on emotions in heroin‐dependent patients.MethodsThis randomized controlled crossover trial included 28 heroin‐dependent ...
Blum, J. +8 more
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Brain Research, 2018
Ankyrin repeat and kinase domain containing 1 (ANKK1) and dopamine receptor D2 (DRD2) gene polymorphisms have long been considered to contribute to susceptibility to heroin dependence.
Jianbo Zhang +10 more
semanticscholar +1 more source
Ankyrin repeat and kinase domain containing 1 (ANKK1) and dopamine receptor D2 (DRD2) gene polymorphisms have long been considered to contribute to susceptibility to heroin dependence.
Jianbo Zhang +10 more
semanticscholar +1 more source
AVERSION THERAPY FOR HEROIN DEPENDENCE
The Lancet, 1968Abstract Suxamethonium chloride (' Scoline ') has been used to produce aversion to the process of preparing for self-injection of heroin. The instruction for self-injection is timed to coincide with the onset of paralysis induced by 30 mg. scoline, and the process is repeated for 5 consecutive days.
I G, Thomson, N H, Rathod
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Buprenorphine and Naloxone for Heroin Dependence
Current Psychiatry Reports, 2000The pharmacology of buprenorphine is unique because of its partial agonist profile at the mu-opioid receptor (ie, high affinity, low intrinsic activity and slow dissociation). This unique profile results in greater safety, less physical dependence, and greater flexibility in dose scheduling.
R E, Johnson, J C, McCagh
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The Socioeconomics of Heroin Dependency
New England Journal of Medicine, 1972Abstract The present production and sale of heroin is an enterprise with gross profits that rivals many industries. Ten kilograms of opium grown in Asia and sold at $25 per kilogram will produce 1 kg of uncut heroin worth $20,000 in the United States. The ultimate aggregate worth of the same kilogram of heroin may be as much as $400,000.
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Prescription of Heroin for the Management of Heroin Dependence
CNS Drugs, 2009The prescription of heroin (diamorphine) for the management of heroin dependence is a controversial treatment approach that was limited to Britain until the 1990s. Since then a number of countries have embarked upon clinical trials of this approach, and it is currently licensed and available in several European countries.
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