Development of mechanical hypersensitivity in rats during heroin and ethanol dependence: Alleviation by CRF1 receptor antagonism [PDF]
Scott Edwards+7 more
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Rare but relevant: The injection of tablet preparations and pulmonary hypertension
Abstract Intravascular injection of dissolved medicinal preparations such as crushed tablets is associated with a risk of injecting particulate material into the vasculature. This particulate material will naturally pass to the lungs where it will be largely filtered out in the pulmonary vascular bed, and in turn, it can result in a range of ...
Johan Duflou
wiley +1 more source
Deficits in Dopamine D2 Receptors and Presynaptic Dopamine in Heroin Dependence: Commonalities and Differences with Other Types of Addiction [PDF]
Diana Martínez+9 more
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What we owe to impaired agents
Journal of Social Philosophy, EarlyView.
Giacomo Floris
wiley +1 more source
ABSTRACT Introduction This study describes opioid and benzodiazepine poisonings in Denmark from 2014 to 2022. The analgesic effect of opioids and sedative effect of benzodiazepines are used to treat pain, insomnia and anxiety disorders and can cause abuse and addiction.
Alba K. V. Sigfredsson+2 more
wiley +1 more source
ABSTRACT Female sex workers as mothers are disproportionately disadvantaged and experience myriad intersecting vulnerabilities, including poverty, physical and mental health challenges, limited access to health care and health care providers, stigma and discrimination, substance use, and histories of trauma.
Rochelle L. Dalla+2 more
wiley +1 more source
Former heroin addicts with or without a history of cocaine dependence are more impulsive than controls [PDF]
David A. Nielsen+6 more
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Astrocytes Mediate Psychostimulant‐Induced Alterations of Spike‐Timing Dependent Synaptic Plasticity
Main Points Cocaine and amphetamine stimulates astrocytes and downregulates the GLT‐1. The dysfunction in GLT‐1 modify EPSP kinetics and modulate STDP, switching LTP to LTD in psychostimulant‐treated mice. These effects were restored by upregulation of GLT‐1.
Samuel Alberquilla+7 more
wiley +1 more source
Failure to identify or effectively manage prescription opioid dependence acted as a gateway to heroin use--buprenorphine/naloxone treatment and recovery in a surgical patient [PDF]
Stephen J. Conroy, Duncan Hill
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Substitution and Complementarity in the Consumption of Alcohol, Cannabis, and Opium
ABSTRACT Understanding the behavior of populations of drug consumers has been and remains a topic of keen interest. Using a unique dataset on 25 districts from Bengal, India, from 1911 to 1925, we analyze whether populations of consumers treat alcohol, cannabis, and opium as economic substitutes or complements in a legal regime.
Siddharth Chandra, Gaurav Doshi
wiley +1 more source