Results 231 to 240 of about 24,412 (283)

AVERSION THERAPY FOR HEROIN DEPENDENCE

The Lancet, 1968
Abstract Suxamethonium chloride (' Scoline ') has been used to produce aversion to the process of preparing for self-injection of heroin. The instruction for self-injection is timed to coincide with the onset of paralysis induced by 30 mg. scoline, and the process is repeated for 5 consecutive days.
I G, Thomson, N H, Rathod
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Buprenorphine and Naloxone for Heroin Dependence

Current Psychiatry Reports, 2000
The pharmacology of buprenorphine is unique because of its partial agonist profile at the mu-opioid receptor (ie, high affinity, low intrinsic activity and slow dissociation). This unique profile results in greater safety, less physical dependence, and greater flexibility in dose scheduling.
R E, Johnson, J C, McCagh
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The Socioeconomics of Heroin Dependency

New England Journal of Medicine, 1972
Abstract The present production and sale of heroin is an enterprise with gross profits that rivals many industries. Ten kilograms of opium grown in Asia and sold at $25 per kilogram will produce 1 kg of uncut heroin worth $20,000 in the United States. The ultimate aggregate worth of the same kilogram of heroin may be as much as $400,000.
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Prescription of Heroin for the Management of Heroin Dependence

CNS Drugs, 2009
The prescription of heroin (diamorphine) for the management of heroin dependence is a controversial treatment approach that was limited to Britain until the 1990s. Since then a number of countries have embarked upon clinical trials of this approach, and it is currently licensed and available in several European countries.
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The Effect Of Heroin Dependence On Resumption Of Heroin Self-Administration In Rats

Drug and Alcohol Dependence, 2014
It has been proposed that relapse vulnerability in previously dependent individuals results from augmentation of drug-induced reinforcement due to repeated associations between the interoceptive properties of the drug and reduction of acute withdrawal distress.To test this hypothesis, male Sprague-Dawley rats self-administered 0.05 mg/kg/inf heroin on ...
Meenu, Minhas, Francesco, Leri
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The medical management of adolescent heroin dependence

Current Psychiatry Reports, 2000
The use of heroin by American adolescents is at its highest levels since the heroin epidemic of the 1960s. This clinical perspective reviews medical issues associated with adolescent heroin dependence. Older, as well as potential newer, treatments for adolescent heroin dependence are discussed.
A B, Rowan, P J, Fudala, J, Mulligan
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Outpatient Methadone Withdrawal for Heroin Dependence

The American Journal of Drug and Alcohol Abuse, 1980
The outcome of outpatient methadone withdrawal reported in 20 published studies during the 1970s varied widely: none to 62% of the patients completed withdrawal, none to 35% became abstinent at termination of withdrawal, and none to 38% were abstinent at follow-up.
J F, Maddux, D P, Desmond, M, Esquivel
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The current status of heroin prescription treatment for heroin dependence

Expert Opinion on Drug Safety, 2005
Heroin prescription (HP) to treat severe heroin dependence has been available to few patients in the UK for several decades with limited, but generally favourable, evaluation. In the last decade, large trials have been reported from two countries, are presently underway in three other countries and under consideration in several other countries.
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Pharmacologic Treatment of Heroin-Dependent Patients

Annals of Internal Medicine, 2000
Patients with heroin dependence frequently present to internists and other physicians for heroin-related medical, psychiatric, and behavioral health problems and often seek help with reducing their heroin use. Thus, physicians should be familiar with the identification and diagnosis of heroin dependence in their patients and be able to initiate ...
P G, O'Connor, D A, Fiellin
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Heroin reward is dependent on a dopaminergic substrate

Life Sciences, 1981
Abstract The rewarding property of heroin was blocked by pretreatment with either naloxone or pimozide, suggesting that this opiate-receptor mediated effect is dependent on a dopaminergic substrate. The involvement of a dopaminergic mechanism in this effect supports the notion that opiates and other sources of reward activate a similar neural ...
M A, Bozarth, R A, Wise
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