Pharmaceuticals, 2023 Practically the entire global population is infected by herpesviruses that establish lifelong latency and can be reactivated. Alpha-herpesviruses, herpes simplex viruses 1 and 2 (HSV-1/HSV-2) and varicella zoster virus (VZV), establish latency in sensory
Tibor Bakacs +2 more
doaj +1 more source
Herpes simplex virus: global infection prevalence and incidence estimates, 2016
Bulletin of the World Health Organization, 2020 Objective To generate global and regional estimates for the prevalence and incidence of herpes simplex virus (HSV) type 1 and type 2 infection for 2016.
Charlotte James +6 more
semanticscholar +1 more source
Amenamevir, a Helicase-Primase Inhibitor, for the Optimal Treatment of Herpes Zoster
Viruses, 2021 Acyclovir, valacyclovir, and famciclovir are used for the treatment of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections. Helicase-primase inhibitors (HPIs) inhibit replication fork progression that separates double DNA strands into ...
K. Shiraki +3 more
semanticscholar +1 more source
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
, 2012 Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Corey W. Hecksel +6 more
core +13 more sources
Risk Factors for Herpes Zoster Infection: A Meta-Analysis
Open Forum Infectious Diseases, 2020 Background The burden of herpes zoster (HZ) is significant worldwide, with millions affected and the incidence rising. Current literature has identified some risk factors for this disease; however, there is yet to be a comprehensive study that pools all ...
F. Marra +3 more
semanticscholar +1 more source
Herpes Simplex Virus-1(HSV-1) causes many diseases including encephalitis, meningitis, keratitis etc. ,also it infects the immunocompromised patients as leukemia and AIDS patients. [PDF]
Kirkuk Journal of Science, 2012 Herpes Simplex Virus-1(HSV-1) causes many diseases including encephalitis, meningitis, keratitis etc. ,also it infects the immunocompromised patients as leukemia and AIDS patients.
Enas A.H. Al-Layla
doaj +1 more source
A 3D human brain–like tissue model of herpes-induced Alzheimer’s disease
Science Advances, 2020 In vitro 3D human brain–like cultures infected with herpes virus develop Alzheimer’s disease characteristics. Alzheimer’s disease (AD) is a neurodegenerative disorder that causes cognitive decline, memory loss, and inability to perform everyday functions.
Dana M. Cairns +5 more
semanticscholar +1 more source
Invasive Obstetric Procedures and Cesarean Sections in Women With Known Herpes Simplex Virus Status During Pregnancy. [PDF]
, 2017 BackgroundNeonatal herpes is a potentially devastating infection that results from acquisition of herpes simplex virus (HSV) type 1 or 2 from the maternal genital tract at the time of vaginal delivery.
Drolette, Linda +7 more
core +1 more source
mBio, 2021 The cGAS/STING/TBK1 (cyclic guanine monophosphate-AMP synthase/stimulator of interferon genes/Tank-binding kinase 1) innate immunity pathway is activated during human cytomegalovirus (HCMV) productive (lytic) replication in fully differentiated cells and
Emily R. Albright +2 more
doaj +1 more source
Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]
, 2015 OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen +8 more
core +2 more sources