Results 21 to 30 of about 204,215 (266)

Felbamate for pediatric epilepsy—should we keep on using it as the last resort?

Frontiers in Neurology, 2022
IntroductionConcerns regarding felbamate adverse effects restrict its widespread use in children with drug-resistant epilepsy. We aimed to examine the efficacy and safety of felbamate in those children and identify the ones who may benefit most from its ...
Shira Rabinowicz, Shira Rabinowicz, Tal Schreiber, Gali Heimer, Gali Heimer, Omer Bar-Yosef, Omer Bar-Yosef, Andreea Nissenkorn, Andreea Nissenkorn, Zohar-Dayan E, Zohar-Dayan E, Leo Arkush, Leo Arkush, Nasrin Hamed, Nasrin Hamed, Bruria Ben-Zeev, Bruria Ben-Zeev, Michal Tzadok, Michal Tzadok   +18 more
doaj   +1 more source

Genital Herpes / Genitalni herpes [PDF]

Serbian Journal of Dermatology and Venerology, 2011
Abstract Genital herpes is a chronic, nearly always active herpes simplex virus (HSV) infection of sacral ganglia, that may appear bilaterally and in more ganglia than previously thought. It represents one of the most prevalent sexually transmitted infections, and the most frequent cause of genital ulcer disease in the general populations of ...
openaire   +1 more source

Analysis of HSV1/2 Infection Reveals an Association between HSV-2 Reactivation and Pregnancy

Viruses
The herpes simplex viruses consist of the strains, HSV-1 and HSV-2, which are prevalent worldwide and lack a definitive cure. We aimed to explore the specific characteristics of HSV 1 and 2 infections, such as differences between gender assigned at birth,
Sara Dovrat, Adar Shabat, Anat Yahav-Dovrat, Zvia Soufiev, Ella Mendelson, Ela Kashi-Zagdoun, Galia Rahav   +6 more
doaj   +1 more source

Role of Polycomb Proteins in Regulating HSV-1 Latency

Viruses, 2013
Herpes simplex virus (HSV) establishes a latent infection within sensory neurons of humans. Latency is characterized by the transcriptional repression of lytic genes by the condensation of lytic gene regions into heterochromatin. Recent data suggest that
David Bloom, Dane Phelan, Harald Messer, Zachary Watson, Adit Dhummakupt   +4 more
doaj   +1 more source

Combination Therapy for the Treatment of Shingles with an Immunostimulatory Vaccine Virus and Acyclovir

Pharmaceuticals, 2023
Practically the entire global population is infected by herpesviruses that establish lifelong latency and can be reactivated. Alpha-herpesviruses, herpes simplex viruses 1 and 2 (HSV-1/HSV-2) and varicella zoster virus (VZV), establish latency in sensory
Tibor Bakacs, Volker Sandig, Imre Kovesdi   +2 more
doaj   +1 more source

Real-Life Experience of Safety Profile of a Rituximab Biosimilar (Reditux®) in Patients at a Rheumatology Center in India

Journal of Marine Medical Society
AIM: The aim of this study was to study the safety profile of a rituximab (RTX) biosimilar Reditux® in patients of rheumatological disorders at a tertiary care hospital in North India.
Ramakant Singh, Vivek Vasdev, Satyam Bhatt, Ashwani Kumar, Abhishek Kumar, Kaushik Roy   +5 more
doaj   +1 more source

HIV Vaccine Mystery and Viral Shell Disorder

Biomolecules, 2019
Hundreds of billions of dollars have been spent for over three decades in the search for an effective human immunodeficiency virus (HIV) vaccine with no success.
Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, Vladimir N. Uversky   +3 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Herpes gestationis

Saudi Medical Journal, 2004
Herpes gestationis, also known as Pemphigoid gestationis, is a rare autoimmune disease of pregnancy. It is characterized by itching and skin lesions. The disease causes prominently maternal discomfort but fetal and neonatal complications have been reported.
Shakeel A, Faiz, Syeda I, Nainar, Mohammed H, Addar   +2 more
openaire   +2 more sources