Results 121 to 130 of about 107,591 (256)

PCR-confirmed severe geographic HSV-1 keratitis associated with systemic JAK inhibitor therapy

Journal of Ophthalmic Inflammation and Infection
Background Janus kinase inhibitors (JAKi) are successfully used for the treatment of refractory systemic autoimmune diseases. However, JAK-inhibition is known to increase the risk of infection. Herpes Zoster reactivation is the most recognised infectious
Dimitri Roels, Elke O. Kreps, Isabeau Houben, Anke Delie, Hilde Lapeere, Bart P. Leroy, Ilse Claerhout, Tessa Kerre   +7 more
doaj   +1 more source

Amenamevir Transfer into Breast Milk in Patients with Herpes Simplex Virus Infection: A Brief Report of a Prospective Multicenter Study

The Journal of Dermatology, EarlyView.
ABSTRACT Patient–initiated therapy (PIT) is a treatment approach in which patients with recurrent herpes simplex self–administer medication at the onset of prodromal symptoms. PIT, which allows patients to receive medication in advance and initiate treatment at any time, is a therapeutic approach that alleviates the burden of urgent clinic visits for ...
Sachi Koinuma, Mikako Goto, Jumpei Saito, Hiroaki Aoki, Satoshi Hayashi, Tomoyoshi Takeshita   +5 more
wiley   +1 more source

Cold Sore, Cold Soul? An Examination of Orolabial Herpes in Film

Revista de Medicina y Cine / Journal of Medicine and Movies, 2016
The sociocultural phenomenon of herpes is attributed to two strains of the herpes simplex virus: herpes simplex virus type 1 (HSV-1) causes orolabial cold sores while herpes simplex virus type 2 (HSV-2) is typically identified in genital lesions, though ...
Alex C. HOLLIDAY, Amanda SALIH, Richard F. Jr. WAGNER   +2 more
doaj  

Dupilumab‐Associated Erythema Multiforme‐Like Eruption With Lichenoid Histology in a Paediatric Patient: A Case Report

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Dupilumab‐associated erythema multiforme and lichenoid eruptions have been previously reported as rare dermatological adverse events. We present an atypical paediatric case of a dupilumab‐associated erythema multiforme‐like eruption in a 5‐year‐old male eczema patient, who developed erythematous targetoid papules and plaques over the upper and
Paul Sun Woo Kim, Jacqueline Tu, Kelvin Truong, Gloria Fong, William Luu, Narinder Kaur, Miriam Fewtrell, Li‐Chuen Wong   +7 more
wiley   +1 more source

Microbicides development program, Tanzania-baseline characteristics of an occupational cohort and reattendance at 3 months.

, 2007
OBJECTIVES: To determine baseline characteristics of an occupational cohort of women in Mwanza City, Tanzania, and factors associated with reattendance at 3 months, in preparation for a microbicide trial.
Vallely, Andrew, Changalucha, John, Ross, David A., Hayes, Richard J., Watson-Jones, Deborah, Hambleton, Ian R, Chirwa, Tobias, Gavyole, Awene, Hayes, Richard J, Balira, Rebecca, Knight, Louise, Hambleton, Ian R., Moyes, Jocelyn, Kasindi, Stella, Pujades-Rodríguez, Mar, Ross, David A, Everett, Dean   +16 more
core   +1 more source

Dupilumab in Paediatric Netherton Syndrome: Two Case Reports and a Review of the Literature

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Netherton Syndrome (NS) is a rare genodermatosis characterised by a triad of ichthyosiform erythroderma, an atopic diathesis, and trichorrhexis invaginata, for which no effective management is currently approved in Australia. Dupilumab has demonstrated considerable effectiveness in the treatment of atopic conditions in the paediatric ...
Jacqueline Tu, Paul Sun Woo Kim, Kelvin Truong, Gloria Fong, William Luu, Li‐Chuen Wong   +5 more
wiley   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

CAR‐HEMATOTOX score to predict risk of poor outcomes with odronextamab in heavily pretreated B‐cell non‐Hodgkin lymphoma

British Journal of Haematology, EarlyView.
High versus low baseline CAR‐HEMATOTOX scores were associated with poorer safety and efficacy outcomes in patients with R/R B‐NHL who received odronextamab in the ELM‐1 and ELM‐2 studies. The CAR‐HEMATOTOX score may provide a readily available measure for identifying patients at risk of inferior clinical outcomes with odronextamab treatment.
Matthew Matasar, David Tucker, Tae Min Kim, Yuan Cheng, Jingjin Li, Saleem Shariff, Hesham Mohamed, Manjusha Namuduri, Aafia Chaudhry, Stefano Luminari   +9 more
wiley   +1 more source

Protective role of Galectin‐3 in prion disease through regulation of microglial PrPSc uptake

Brain Pathology, EarlyView.
Galectin‐3 (Gal3) is induced in reactive microglia during prion disease and promotes microglial uptake of PrPSc. Gal3 deficiency reduces prion sequestration and accelerates disease progression, revealing a protective role for Gal3. Abstract Microglia constitute a major innate defense mechanism against prion infection; however, the molecular pathways ...
Natallia Makarava, Tarek Safadi, Narayan P. Pandit, Olga Mychko, Olga Bocharova, Alexey Shevelkin, Kara Molesworth, Marta M. Lipinski, Ilia V. Baskakov   +8 more
wiley   +1 more source