Results 131 to 140 of about 153,585 (315)

GLUT1 Deficiency Syndrome with Coexistent Movement Disorder and Anemia

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Sangeetha Yoganathan   +12 more
wiley   +1 more source

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

The Sensitivity of Adenovirus and Herpes simplex virus to Honey

open access: yes, 2009
Honey has been used for centuries as a medicine to treat various ailments and infections. A large amount of research has established that honey has potent antibacterial activity.
Littlejohn, Emma Sophie Vout
core  

Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time‐to‐resolution

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth   +5 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

open access: yesBritish Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu   +6 more
wiley   +1 more source

Oncolytic Vaccinia Virus‐HSP70‐shRNA Amplifies Viral Replication, ROS/Autophagy, and Immunity to Fight Colorectal Cancer

open access: yesCancer Science, EarlyView.
OncoVV‑shHSP70, a vaccinia virus silencing HSP70, demonstrated potent antitumor efficacy in colorectal cancer cell lines, as well as in syngeneic, xenograft, and humanized mouse models. In cell lines, oncoVV‑shHSP70 promoted viral oncolysis and cytokine production through a self‑reinforcing cycle of ROS‑autophagy. In both CT26 and SW620‑humanized mouse
Rentao Yuan   +8 more
wiley   +1 more source

HERPES-SIMPLEX VIRUS FROM TRIGEMINAL GANGLION

open access: yes, 1973
HERPES-SIMPLEX VIRUS FROM TRIGEMINAL ...
DO WHITE (14583035)   +2 more
core  

Long-term impact of acyclovir suppressive therapy on genital and plasma HIV RNA in Tanzanian women: a randomized controlled trial.

open access: yes, 2010
BACKGROUND: Herpes simplex virus (HSV) suppressive therapy reduces genital and plasma human immunodeficiency virus type 1 (HIV-1) RNA over periods up to 3 months, but the long-term effect is unknown.
Mugeye, Kokugonza   +12 more
core   +1 more source

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

open access: yesCancer Science, EarlyView.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi   +11 more
wiley   +1 more source

Herpes simplex keratitis: challenges in diagnosis and clinical management

open access: yes, 2017
Tayaba N Azher,1 Xiao-Tang Yin,1 Deena Tajfirouz,1 Andrew JH Huang,2 Patrick M Stuart1 1Department of Ophthalmology, Saint Louis University, 2Department of Ophthalmology and Visual Sciences, Washington University, St Louis, MO, USA Abstract: Herpes ...
Tajfirouz D   +4 more
core  

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