Results 181 to 190 of about 107,591 (256)

Clinically suspected central nervous system Richter transformation presenting with progressive psychiatric symptoms: A case report

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.
Abstract Background Central nervous system (CNS) involvement associated with Richter transformation (RT) is a rare complication of chronic lymphocytic leukemia (CLL). Neurological manifestations are heterogeneous. To our knowledge, no previous reports have described CNS RT presenting predominantly with psychiatric and behavioral symptoms.
Tetsuro Ishida, Yusuke Sugama
wiley   +1 more source

A case of acute lithium encephalopathy associated with elevated myelin basic protein levels in cerebrospinal fluid

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.
Abstract Background Acute lithium intoxication can cause severe central nervous system (CNS) manifestations, sometimes leading to long‐term sequelae known as the syndrome of irreversible lithium‐effectuated neurotoxicity (SILENT). However, its underlying pathophysiology remains unclear.
Teruo Yokoyama   +3 more
wiley   +1 more source

Diagnostic and Therapeutic Insights From a Case Series of Melkersson‐Rosenthal Syndrome With a Complete Clinical Triad: Unmasking the Overlooked Syndrome

open access: yesClinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Recurrent facial nerve palsy, particularly when alternating sides and accompanied by orofacial edema, should raise suspicion for Melkersson–Rosenthal syndrome. Recognition of fissured tongue as part of the clinical triad may facilitate timely diagnosis, avoid unnecessary investigations, and enable appropriate corticosteroid treatment.
Zoran Dudvarski   +6 more
wiley   +1 more source

Plant‐Derived Probiotics From Fermented Foods: Current Evidence on Antiviral Mechanisms and Gut–Lung Axis Modulation

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
Plant‐derived probiotics from fermented foods exert anti‐respiratory virus effects via immune regulation, antiviral metabolites, and gut–lung axis, highlighting their advantages, key technologies, and application prospects. ABSTRACT Respiratory viral infections represent a major global public health threat, causing widespread morbidity, mortality, and ...
Yinghao Xing   +6 more
wiley   +1 more source

Polyomavirus Drives Cerebellar Lesions in AIDS Monkeys With Ataxia

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Chronic SIV‐infected macaques with ataxia develop severe cerebellar lesions driven by simian polyomavirus 40 (SV40) infection. SV40 preferentially infects cerebellar granule cells, inducing pyroptosis and an aberrant proliferative state. Pyroptotic neuronal injury promotes microglial recruitment and activation, amplifying local neuroinflammation and ...
Tian‐Zhang Song   +9 more
wiley   +1 more source

Metabolic Screening and In Silico Investigation of Eucalyptus globulus Essential Oil Bioactives Against DENV‐2 Envelope Protein

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Network pharmacology and molecular docking identify bioactive compounds from Eucalyptus globulus essential oil with potential activity against dengue virus, highlighting 70 shared targets and DENV‐2‐associated pathways. Globulol and eucalyptol show strong binding to DENV‐2 receptors, with favorable drug‐likeness and toxicity profiles, supporting their ...
Arslan Afzal   +8 more
wiley   +1 more source

Systems Pharmacology Investigation of Phytochemicals From Scilla peruviana L.: Integrated Gas Chromatography–Mass Spectrometry Profiling, Network Pharmacology, and Molecular Docking Reveal Potential Anti‐Inflammatory Mechanisms

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
This study aims to characterize the volatile and fatty acid constituents of Scilla peruviana and investigate their potential anti‐inflammatory mechanisms. Volatile compounds are identified by headspace solid‐phase microextraction (HS‐SPME) coupled with GC–MS, whereas fatty acids are analyzed by GC–MS following derivatization.
Roukia Zatout   +2 more
wiley   +1 more source

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

open access: yesChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature

open access: yesReviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Varicella zoster virus (VZV) and herpes simplex virus (HSV) are major causes of viral meningitis and encephalitis. Standard intermittent intravenous acyclovir requires hospitalisation, reducing patient comfort and prolonging admissions. Continuous infusion may maintain therapeutic plasma and cerebrospinal fluid (CSF) concentrations while ...
Irene G. Manders   +7 more
wiley   +1 more source

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