Abstract Problem Maternal obesity and viral infection induce placental inflammation, but how their co‐exposure influence fetoplacental development remains unclear. We hypothesised that maternal high fat (HF) diet and viral infection would independently induce placental inflammation and lipid peroxidation, reduce antioxidant defence, and cellular ...
Thaina Ferraz +4 more
wiley +1 more source
SGK2 mediates apoptosis in herpes simplex keratitis by suppressing protective autophagy via the mTOR pathway. [PDF]
Liu S +6 more
europepmc +1 more source
Infection control in the brain and the eye
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
EEG-motor correlation as early Alzheimer's disease index in herpes simplex virus type-1-infected mice. [PDF]
D'Amelio C +20 more
europepmc +1 more source
Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley +1 more source
Genital Immune Correlates of Seroprevalent and Seroincident Herpes Simplex Type 2 Infection Among Women Who Sell Sex in Nairobi, Kenya. [PDF]
Udayakumar S +16 more
europepmc +1 more source
ABSTRACT Background Cognitive impairment is common in bipolar disorder (BD), but the underlying pathophysiology remains unclear. This systematic review aimed to (1) summarize all literature describing relationships of biofluid biomarkers and cognition in BD and (2) identify which biofluid biomarkers correlate most consistently with cognition in BD ...
Alexandra J. M. Beunders +21 more
wiley +1 more source
Case Report: Conservative management of herpes simplex keratitis with corneal perforation and anterior chamber collapse. [PDF]
Xie W, Tian T, Ying L.
europepmc +1 more source
Fixed drug eruption misdiagnosed as herpes simplex virus infection. [PDF]
Moschella A, Gifford F.
europepmc +1 more source
Sex-specific biological susceptibility and sexual mixing patterns in herpes simplex virus type 2 transmission: a mathematical modeling study. [PDF]
Hachem H, Ayoub HH, Abu-Raddad LJ.
europepmc +1 more source

