Results 211 to 220 of about 153,585 (315)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, Volume 13, Issue 31, 4 June 2026.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Dynamics of Paraspeckle Components in Herpes Simplex Virus 1 (HSV-1)-Infected Human Neuronal Cells. [PDF]

Viruses
Filipponi C, Bloom DC, Gambotto C, Wallace CT, Milosevic J, Watkins SC, Buckley S, Wesesky MA, Nimgaonkar VL, D'Aiuto L.   +9 more
europepmc   +1 more source

Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy

Aggregate, Volume 7, Issue 6, June 2026.
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao, Dong Wang, Lei Wang, Hongkai Zhang, Yue Sun, Dan Ding   +5 more
wiley   +1 more source

Reduction of angiogenesis in chorioallantoic membrane xenografted hepatocellular carcinomas by treatment with a decorin-expressing herpes simplex virus vector. [PDF]

Virol J
Frejborg F, Koivisto O, Huttunen R, Rosenholm JM, Zhang H, Järveläinen H, Hukkanen V.   +6 more
europepmc   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, Volume 99, Issue 6, Page 1468-1479, June 2026.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

Observation of Changes in Dendritic Cells in Patients with Herpes Simplex Stromal Keratitis Using In Vivo Confocal Microscopy. [PDF]

Biomedicines
Sun Z, Que L, Xiao F, Liu W, Liu Y.
europepmc   +1 more source

A Mechanistic Model of rAAV Production in Synthetic Cell Lines

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1684-1694, June 2026.
ABSTRACT The recombinant adeno‐associated virus (rAAV) is a widely used vector for gene therapy. Its manufacturing faces significant challenges in producing the large quantities of vectors needed for clinical applications and reducing empty particles.
Prahalad Srinivasan, Han‐Jung Kuo, Yu‐Chieh Lin, Yen‐An Lu, Wei‐Shou Hu, Qi Zhang   +5 more
wiley   +1 more source

Erythema Nodosum Leprosum Triggered by Herpes Simplex Infection: A Case Report. [PDF]

Cureus
Al-Anbagi U, Nashwan AJ, Al Hyassat S, Assaf FJ, Abdulmajeed HA, Mohamed AH.   +5 more
europepmc   +1 more source

A Diagnostic Challenge: From Suspected Ischemic Stroke to Confirmed Herpetic Encephalitis

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Multimodal neuroimaging in a case of HSV‐1 encephalitis mimicking malignant MCA stroke: from initial CT findings misinterpreted as large territorial infarction, through decompressive craniectomy for refractory intracranial hypertension, to MRI confirmation of non‐territorial haemorrhagic encephalitis prompting CSF analysis and acyclovir therapy ...
Mafalda Dias Neves, Miguel Gonçalves Pereira, Natacha Silveira, Susana Barbosa, José Maria Matos Sousa, Eduarda Pereira, Elisabete Monteiro   +6 more
wiley   +1 more source