Herpes simplex virus triggers and then disarms a host antiviral response [PDF]
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R +5 more
core +1 more source
Herpes Simplex Virus Infection Mimicking Bullous Disease in an Immunocompromised Patient
Immunodeficient patients are at risk of developing extended or atypical herpes simplex virus infections, which can be easily misdiagnosed. We present the case of a 79-year-old, treatment-induced (oral corticosteroid), immunocompromised female with an ...
Anne L.Y. Lecluse +1 more
doaj +1 more source
Abstract Lesions of the pancreas induced by viral infection have drawn relatively little attention because of their low incidence, and the histopathologic features of viral pancreatitis have not been fully elucidated. We report the autopsy findings of 2 patients, a 59-year-old woman with allergic granulomatous angiitis and a 73-year ...
Masayuki, Shintaku +4 more
openaire +2 more sources
Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis [PDF]
Despite antiviral treatment and advances in critical care, the Herpes simplex encephalitis (HSE) still has a poor outcome in a significant portion of patients.
Baršić, Bruno, Kutleša, Marko
core +1 more source
Urethral Orifice Genital Herpes Caused by HSV-1 in a Female Patient: A Case Report
. Introduction:. Genital herpes is one of the most common sexually transmitted infections worldwide. Most genital herpes occur on the genitalia, perineum, buttocks, upper thighs, or perianal areas.
Jia-Yi Yang, Xiao-Hui Mo, Xiu-Li Wang
doaj +1 more source
Seroprevalence, predictors and estimated incidence of maternal and neonatal Herpes Simplex Virus Type 2 infection in semi-urban women in Kilifi, Kenya [PDF]
Background: Herpes Simplex Virus type 2 (HSV-2) has public health importance as a leading cause of genital ulcers, a co-factor in HIV-1 acquisition and transmission and as a cause of neonatal herpes infections.
Awuondo Ken +35 more
core +2 more sources
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu +16 more
core +1 more source
Effect of Blended Learning Program on Awareness of Parents’ Caring for Children with Herpes Simplex [PDF]
Background: Infection with the Herpes Simplex Viruses (HSV) type 1 and 2 is fairly frequent. While HSV-1 infections have traditionally been linked with oral lesions and HSV-2 infections with genital illness, both virus serotypes can infect either region.
Fatma Abdellah Mohamed +2 more
doaj +1 more source
Seroepidemiological study of herpes simplex virus types 1 and 2 in Brazil, Estonia, India, Morocco, and Sri Lanka [PDF]
Background: The association between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) and the development of HSV vaccines have increased interest in the study of HSV epidemiology.Objectives: To estimate the age and sex specific ...
Rbai, M +16 more
core +1 more source
Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre +16 more
core +1 more source

