Results 81 to 90 of about 128,307 (266)

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

open access: yesiMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu   +7 more
wiley   +1 more source

Disseminated anogenital Herpes Simplex With Encephalitis

open access: yesIndian Journal of Dermatology, 2001
A case of herpes simplex encephalitis secondary to primary anogenital herpes simplex is being reported for its rarity.
Kaur Sukhjot   +2 more
doaj  

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang   +3 more
wiley   +1 more source

A preterm neonate with infantile liver failure syndrome 1 due to leucyl‐tRNA synthetase 1 gene (LARS1) mutations with a histopathologic phenotype of neonatal hemochromatosis

open access: yesJPGN Reports, EarlyView.
Abstract We report a case of a premature, growth‐restricted female infant with feeding intolerance and coagulopathy, treated initially for sepsis, who progressed to neonatal acute liver failure and end‐stage hepatic encephalopathy after a prolonged hospitalization with extensive diagnostic evaluation, and was found by autopsy to have histopathologic ...
Adrienne Bruder   +3 more
wiley   +1 more source

Analysis of clinical characteristics and factors influencing herpes simplex virus keratitis

open access: yesFrontiers in Medicine
ObjectiveTo investigate the clinical characteristics and factors associated with herpes simplex virus keratitis.MethodsPatients with herpes simplex virus keratitis who came to our hospital from January 2018 to June 2022 were selected and divided into a ...
Shuai Zhang   +6 more
doaj   +1 more source

PCR-confirmed severe geographic HSV-1 keratitis associated with systemic JAK inhibitor therapy

open access: yesJournal of Ophthalmic Inflammation and Infection
Background Janus kinase inhibitors (JAKi) are successfully used for the treatment of refractory systemic autoimmune diseases. However, JAK-inhibition is known to increase the risk of infection. Herpes Zoster reactivation is the most recognised infectious
Dimitri Roels   +7 more
doaj   +1 more source

Cold Sore, Cold Soul? An Examination of Orolabial Herpes in Film

open access: yesRevista de Medicina y Cine / Journal of Medicine and Movies, 2016
The sociocultural phenomenon of herpes is attributed to two strains of the herpes simplex virus: herpes simplex virus type 1 (HSV-1) causes orolabial cold sores while herpes simplex virus type 2 (HSV-2) is typically identified in genital lesions, though ...
Alex C. HOLLIDAY   +2 more
doaj  

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal   +2 more
wiley   +1 more source

Bevacizumab‐Associated Eczema Herpeticum in Metastatic Ovarian Carcinoma: A Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Eczema herpeticum (EH) is a rare but potentially life‐threatening cutaneous infection caused by herpes simplex virus (HSV), classically associated with atopic dermatitis. Its occurrence in oncology patients receiving anti‐angiogenic targeted therapy and cytotoxic chemotherapy is exceedingly uncommon.
Mandeep Dutta Joshi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy