Results 151 to 160 of about 108,460,457 (303)
Inborn errors of immunity in children with neuroinflammation
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu +5 more
wiley +1 more source
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid +8 more
wiley +1 more source
Untersuchung viraler Genfunktionen im Replikationszyklus des Herpes Simplex Virus Typ 1 [PDF]
Dissertation zum Thema "Untersuchung viraler Genfunktionen im Replikationszyklus des Herpes Simplex Virus Typ 1".PhD-studies on "analysis of viral gene function within the replication cycle of herpes simplex virus type 1"
Leege, Tobias
core
ABSTRACT Background Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) remain major global public health concerns. Oral lesions are often among the earliest manifestations of HIV, placing dentists at the forefront of early detection and management.
Tuğba Aydoğdu, Berkant Sezer
wiley +1 more source
OZAWA, Shigeru +4 more
openaire +3 more sources
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
Transgenic selection and underlying mechanisms in apicomplexan parasites
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas +4 more
wiley +1 more source
Prevalence of Oral Mucosal Lesions in Finnish Adults—Findings From the Healthy Finland Survey
ABSTRACT Objectives Oral mucosal lesions (OMLs) are abnormal findings of the oral mucosa. OMLs can be a localized disease due to trauma or infections, a manifestation of systemic or dermatological disease, or a sign of neoplasia. The aim of this study was to assess the prevalence of OMLs among Finnish adults.
Mirjami J. Rintala +5 more
wiley +1 more source

