Association between malaria exposure and Kaposi's sarcoma-associated herpes virus seropositivity in Uganda. [PDF]
OBJECTIVE: Unlike other herpes viruses, Kaposi's sarcoma-associated herpes virus (KSHV) is not ubiquitous worldwide and is most prevalent in sub-Saharan Africa. The reasons for this are unclear. As part of a wider investigation of factors that facilitate
Cose, Stephen+8 more
core +3 more sources
A Comprehensive Overview of Epidemiology, Pathogenesis and the Management of Herpes Labialis
Herpes labialis remains exceedingly prevalent and is one of the most common human viral infections throughout the world. Recurrent herpes labialis evolves from the initial viral infection by herpes simplex virus type 1 (HSV-1) which subsequently presents
Divya Gopinath+3 more
doaj +2 more sources
Prediction of herpes virus infections after solid organ transplantation: a prospective study of immune function [PDF]
IntroductionHerpes virus infections are a major concern after solid organ transplantation and linked to the immune function of the recipient. We aimed to determine the incidence of positive herpes virus (cytomegalovirus (CMV), Epstein-Barr virus (EBV ...
Dina Leth Møller+20 more
doaj +2 more sources
Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial
This investigator-initiated, phase 2, single-arm trial primarily assessed the efficacy of G47∆, a triple-mutated, third-generation oncolytic herpes simplex virus type 1, in 19 adult patients with residual or recurrent, supratentorial glioblastoma after ...
T. Todo+6 more
semanticscholar +1 more source
Current Drugs to Treat Infections with Herpes Simplex Viruses-1 and -2
Herpes simplex viruses-1 and -2 (HSV-1 and -2) are two of the three human alphaherpesviruses that cause infections worldwide. Since both viruses can be acquired in the absence of visible signs and symptoms, yet still result in lifelong infection, it is ...
Lauren A. Sadowski+3 more
doaj +1 more source
The World of Antiherpetic Vaccines and Drugs, 2022
The world of antiherpetics has grown by leaps and bounds since the discovery of what would become the first antiherpetic drug in 1964 [...]
Barry J. Margulies
doaj +1 more source
Pathogenesis and virulence of herpes simplex virus
Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital herpes, herpes stromal keratitis, meningitis and encephalitis.
Shuyong Zhu, A. Viejo-Borbolla
semanticscholar +1 more source
Pioneer factors in viral infection
Pioneer factors are transcription factors sharing the fascinating ability to bind to compact chromatin and thereby alter its transcriptional fate. Most pioneer factors are known for their importance during embryonic development, for instance, in inducing
Eva Neugebauer+9 more
doaj +1 more source
Towards a comprehensive view of the herpes B virus
Herpes B virus is a biosafety level 4 pathogen and widespread in its natural host species, macaques. Although most infected monkeys show asymptomatic or mild symptoms, human infections with this virus can cause serious neurological symptoms or fatal ...
Jiangling Lu+10 more
doaj +1 more source
Herpes B virus: History, zoonotic potential, and public health implications
Recently, death from herpes B virus (Cercopithecine Herpesvirus 1) infection was reported in China, reminding us to be alert to the risk of transmission and infection with herpes B virus.
Geng Hu+4 more
doaj +1 more source