Results 131 to 140 of about 2,028,368 (401)

Primary Generalized Infection Caused by Herpes Simplex Virus [PDF]

open access: green, 1952
W. H. J. Baker   +2 more
openalex   +1 more source

Recurrent fexuprazan‐induced liver injury following unintentional re‐exposure

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Fexuprazan, a potassium‐competitive acid blocker, is increasingly used for the treatment of gastroesophageal reflux disease in South Korea. While generally well tolerated, data regarding its hepatotoxic potential are scarce. We report a case of idiosyncratic drug‐induced liver injury in a 61‐year‐old woman following 2 months of fexuprazan therapy.
Sook Jin Seong   +5 more
wiley   +1 more source

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]

open access: yes, 2018
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan   +3 more
core   +2 more sources

Some Properties of Herpes Simplex Virus [PDF]

open access: bronze, 1953
Klaus Munk, W. W. Ackermann, Hilda Kurtz
openalex   +1 more source

Transcriptomic functional characterization of recombinant adeno‐associated virus producing cell line adapted to suspension‐growth

open access: yesBiotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo   +6 more
wiley   +1 more source

Autophagy Quantification and STAT3 Expression in a Human Skin Organ Culture Model for Innate Immunity to Herpes Zoster

open access: yesFrontiers in Microbiology, 2018
The goal of this project was to document the autophagy response in human neonatal skin organ culture (SOC) after infection with varicella-zoster virus (VZV).
Erin M. Buckingham   +4 more
doaj   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

open access: yesCancer Communications, EarlyView.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang   +3 more
wiley   +1 more source

Purification of Herpes Simplex Virus

open access: yesJournal of General Virology, 1974
Summary Herpes simplex virus was highly purified from host cell material with little loss of infectivity by the combination of isopycnic centrifuging in a three layered silica gradient and rate zonal centrifuging in dextran T 70 gradient. By layering three solutions of colloidal silica (24, 18 and 12%, w/v) on top of each other in the centrifuge tube ...
Jonas Blomberg, A. Vahlne
openaire   +3 more sources

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

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