Results 311 to 320 of about 2,028,368 (401)

cGAS–STING Pathway Activation Enhances Antitumor Effect of Talaporfin Photodynamic Therapy Through ROS Production

Cancer Science, EarlyView.
This study investigates the role of STING in photodynamic therapy (PDT) using talaporfin sodium. STING knockout reduced ROS generation and therapeutic efficacy, while combining a STING agonist with PDT enhanced antitumor effects. These findings suggest that STING regulates ROS homeostasis and can potentiate PDT outcomes.
Makiko Sasaki, Mamoru Tanaka, Yasunari Sasaki, Yuki Kojima, Taketo Suzuki, Hirotada Nishie, Shigeki Fukusada, Naomi Sugimura, Keiji Ozeki, Takaya Shimura, Eiji Kubota, Hiromi Kataoka   +11 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Long-term performance of show-jumping horses and relationship with severity of ataxia and complications associated with myeloencephalopathy caused by equine herpes virus-1. [PDF]

J Vet Intern Med
de la Cuesta-Torrado M, Velloso Alvarez A, Neira-Egea P, Cuervo-Arango J.   +3 more
europepmc   +1 more source

Serological Relationships among Viruses of the Herpes Group

, 1967
Derek Watson, P. Wildy, B. A. M. Harvey, W. I. H. Shedden   +3 more
openalex   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

First study of the detection of Human Herpes Virus-8 and major blood-borne viruses in iranian patients with SLE: A cross-sectional study. [PDF]

New Microbes New Infect
Soltani L, Hashempour A, Moayedi J, Feili M, Musavi Z, Nazarinia MA.   +5 more
europepmc   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source

Herpes virus entry mediator signaling blockade produces mortality in neonatal sepsis through induced cardiac dysfunction. [PDF]

Front Immunol
Wakeley ME, Denning NL, Jiang J, De Paepe ME, Chung CS, Wang P, Ayala A.   +6 more
europepmc   +1 more source

Acute Liver Failure and Human Herpesvirus 6 Infection: Reactivation in Immunoparesis? [PDF]

GE Port J Gastroenterol
Marques Correia I, Rodrigues AI, Henriques A, Ferreira DM, Cipriano MA, Lima J.   +5 more
europepmc   +1 more source

Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16431 Abstract Antenatal destructive events affecting the central nervous system of the foetus lead to disruptive brain lesions that are often associated with impaired neurodevelopment.
Ana Alarcón, Nuria Carreras, Tobias Muehlbacher, Dídac Casas‐Alba, Roberta Arena, Paola Roca‐Llabrés, Juan Navarro‐Morón, Linda S. de Vries, Paul Govaert, the EurUS.Brain group, Thais Agut, Roberta Arena, Ana Alarcón, Juan Arnáez, Marco Bartocci, Isabel Benavente‐Fernández, María Carmen Bravo, Fernando Cabañas, Nuria Carreras, Olivier Claris, Jeroen Dudink, Monica Fumagalli, Alfredo García‐Alix, Paul Govaert, Sandra Horsch, Simón Lubián, Tobias Muehlbacher, Alessandro Parodi, Adelina Pellicer, Luca Ramenghi, Charles C. Roehr, Simone Schwarz, Sylke Steggerda, Eva Valverde   +33 more
wiley   +1 more source