Results 51 to 60 of about 1,234,222 (260)

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Zosteriform spread of herpes simplex virus as a model of recrudescence and its use to investigate the role of immune cells in prevention of recurrent disease [PDF]

, 1984
During the development of a zosteriform rash, which occurs after flank inoculation of BALB/c mice with herpes simplex virus, clinically normal skin becomes infected via nerve endings.
Simmons, Anthony, Nash, Anthony
core  

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

Advanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du, Liping Wang, Sujing Diao, Juan Li, Lei Zhao, Yan Yan, Haimin Li, Weiren Dong, Wei Wu, Jinyan Gu, Jiyong Zhou   +10 more
wiley   +1 more source

Seroprevalence of Anti- Herpes Simplex Virus Type2 IgG, IgM Antibodies Among Pregnant Women in Diyala Province

Diyala Journal of Medicine, 2019
Background: Herpes simplex virus type 2 (HSV-2) is the leading cause of genital ulcer disease worldwide. The acquisition of genital herpes during pregnancy has been associated with spontaneous abortion, prematurity, and congenital and neonatal herpes.
Abul-Razak SH Hasan , Abbas A Al-Duliami , Asmaa Haseeb Hwaid , Wasan A Mageed , Zeina Gany Fadeel   +4 more
doaj   +2 more sources

Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. [PDF]

, 2008
BACKGROUND: Infection with herpes simplex virus type 2 (HSV-2) is associated with an increased risk of acquiring infection with the human immunodeficiency virus (HIV).
HSV trial team, Clare Tanton, Tim Clayton, Weiss, Helen A, Watson-Jones, Deborah, Hambleton, Ian, Louise Knight, Steering and Data Monitoring Committees, Laurent Belec, Kokugonza Mugeye, Tanton, Clare, Le Goff, Jerome, Deborah Watson-Jones, Ross, David, Knight, Louise, Baisley, Kathy, Hayes, Richard, Richard Hayes, Everett, Dean, Clayton, Tim, Kathy Baisley, Mugeye, Kokugonza, Changalucha, John, Mary Rusizoka, Helen A. Weiss, Jerome Le Goff, John Changalucha, Dean Everett, Balira, Rebecca, Ian Hambleton, Rebecca Balira, Rusizoka, Mary, David Ross, Belec, Laurent   +33 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Fibrillarin Resists Cellular Senescence Via SIRT1‐Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin, Hong Liu, Ling Gao, Lei Liu, Ji‐Bin Liu, Xiaoxia Jin, Ming‐Song Wang, Dan Liu, Li Feng, Wen‐Lian Chen   +9 more
wiley   +1 more source

Seroprevalence and seroincidence of herpes simplex virus type 1 and herpes simplex virus type 2 infections in a cohort of adolescents in Italy

, 2004
OBJECTIVE: The objective of this study was to improve the knowledge on the epidemiology of herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) in Italy.
PALU', GIORGIO, GRILLI G, SULIGOI B, TORRI A, THE ITALIAN HERPES MANAGEMENT FORUM, TANZI E   +5 more
core   +2 more sources

Herpes Zoster Ophthalmicus in HIV/AIDS

Community Eye Health Journal, 2003
Herpes zoster is a common infection caused by the human herpes virus 3, the same virus that causes chickenpox. It is a member of herpes viridae, the same family as the herpes simplex virus, Epstein- Barr virus, and cytomegalovirus.
Boateng Wiafe MD MSc
doaj