Results 61 to 70 of about 1,234,222 (260)

Risk of HSV-2 Acquisition Among Women with Bacterial Vaginosis: Systematic Review and Meta-Analysis

Viruses
Objective: Bacterial vaginosis is a dysbiosis of the vaginal microbiome, typically characterized by a loss of Lactobacillus. Lactobacillus plays a crucial role in vaginal immunity and protection against sexually transmitted infections.
Taylor N. Whitt, Alexis Heath, D’Atra J. Hill, Douglas K. Brubaker, Christina Farr Zuend   +4 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Beta herpes viruses in patients with cutaneous graft-versus-host disease

Журнал инфектологии, 2015
Graft-versus-host disease is a major complication of allogenic bone marrow transplantation. Beta herpes viruses’ role in pathogenesis and prognosis of graft-versus-host disease is significant.
V. V. Baykov, I. S. Moiseev, A. Yu. Petrova, E. V. Lisukova, I. E. Belousova, I. O. Smirnova, I. N. Telichko   +6 more
doaj   +1 more source

Population-level effect of potential HSV2 prophylactic vaccines on HIV incidence in sub-Saharan Africa. [PDF]

, 2009
Herpes simplex virus type-2 (HSV2) infection increases HIV transmission. We explore the impact of a potential prophylactic HSV2 vaccination on HIV incidence in Africa using STDSIM an individual-based model.
Orroth, K. K., Buve, A, Hayes, Richard J., Weiss, Helen A, Hayes, R. J., Glynn, Judith R., Glynn, Judith R, Weiss, H. A., White, Richard G, Hayes, Richard J, White, Richard G., Bakker, R., Weiss, Helen A., Orroth, Kate K, Buvé, Anne, Freeman, EE, Glynn, J. R., Weiss, HA, White, R. G., Freeman, Esther E, Freeman, Esther E., Freeman, E. E., Buvé, A., White, RG, Glynn, JR, Orroth, KK, Orroth, Kate K., Bakker, Roel, Hayes, RJ   +28 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Association between dietary inflammation index and herpes simplex virus I and II: A cross-sectional study.

PLoS ONE
IntroductionWe aimed to fill the research gap between DII and herpes simplex virus infection among adults in the US by analyzing the association between dietary inflammatory index and herpes simplex virus and to provide new ideas for herpes simplex virus
Jing Luo, En-Hui Liu, Hao-Kai Chen, Xiang-Ping He, Tong Chen, Yu-Qi Hu, Xu-Guang Guo   +6 more
doaj   +1 more source

Herpes simplex ulcerative esophagitis in healthy children

The Saudi Journal of Gastroenterology, 2011
Herpes simplex virus is a common cause of ulcerative esophagitis in the immunocompromised or debilitated host. Despite a high prevalence of primary and recurrent Herpes simplex virus infection in the general population, Herpes simplex virus esophagitis ...
Abdulrahman A Al-Hussaini, Mosa A Fagih
doaj   +1 more source

Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis [PDF]

, 2012
Despite antiviral treatment and advances in critical care, the Herpes simplex encephalitis (HSE) still has a poor outcome in a significant portion of patients.
Baršić, Bruno, Kutleša, Marko
core   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source