Results 111 to 120 of about 150,458 (253)
Viral infection arrests host cells in the S phase, which promotes vDNA synthesis and vRC formation, further facilitating viral recruitment of RNA Pol II to preferentially transcribe viral genes. ABSTRACT Herpesviruses rely on host RNA polymerae II (RNA Pol II) for their mRNA transcription, yet the mechanisms of which has been poorly defined, while ...
Qiqi Yang+16 more
wiley +1 more source
An experimental evaluation of a loop versus a reference design for two-channel microarrays [PDF]
Motivation: Despite theoretical arguments that socalled "loop designs" of two-channel DNA microarray experiments are more efficient, biologists keep on using "reference designs".
C. P. Smith+16 more
core +2 more sources
Organoid Models to Study Human Infectious Diseases
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu+4 more
wiley +1 more source
Herpesvirus saimiri-induced proteins in lytically infected cells. I. Time-ordered synthesis [PDF]
The addition of TPA (phorbol-12-myristate-13-acetate) to cultures during the lytic infection with herpesvirus saimiri led to an enhanced and accelerated production of polypeptides induced by H.
Modrow, Susanne, Wolf, Hans J.
core +1 more source
Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina+8 more
wiley +1 more source
Herpesviruses and Intermediate Filaments: Close Encounters with the Third Type
Intermediate filaments (IF) are essential to maintain cellular and nuclear integrity and shape, to manage organelle distribution and motility, to control the trafficking and pH of intracellular vesicles, to prevent stress-induced cell death, and to ...
Laura Hertel
doaj +1 more source
A New Member of the Herpesvirus Group Isolated from South American Marmosets [PDF]
Joseph L. Melnick+4 more
openalex +1 more source
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder+4 more
wiley +1 more source
Kaposi's sarcoma-associated herpesvirus oncoprotein K13 protects against B cell receptor induced growth arrest and apoptosis through NF-κB activation [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) has been linked to the development of Kaposi's sarcoma, primary effusion lymphoma and multicentric Castleman's disease (MCD). We have characterized the role of KSHV-encoded viral FLICE inhibitory protein K13
Ahmad+53 more
core +1 more source