Results 141 to 150 of about 817,417 (222)
ABSTRACT Background Allergic rhinitis (AR) represents a highly prevalent inflammatory disorder of the nasal mucosa, but molecular indicators capable of capturing its disease‐specific transcriptional features remain insufficiently defined. This study aimed to identify cell adhesion‐related diagnostic biomarkers for AR and to investigate their immune ...
Guoshun He, Liying Zhang
wiley +1 more source
“Novel” Triggers of Herpesvirus Reactivation and Their Potential Health Relevance
Tobias Stoeger, Heiko Adler, Heiko Adler
doaj +1 more source
ABSTRACT Cytomegalovirus (CMV) is a prevalent herpesvirus that remains typically asymptomatic in immunocompetent individuals but can cause severe, potentially life‐threatening disease in immunocompromised patients. This study assessed the impact of CMV‐associated lower respiratory tract infections (LRTIs), diagnosed by polymerase chain reaction (PCR ...
Theodora Zouvani +10 more
wiley +1 more source
Herpesviruses show consistency in their nuclear egress-associated induction of lamina-depleted areas as measured in an autofluorescent reporter cell model. [PDF]
Dhotre K +3 more
europepmc +1 more source
Posttranslational Modifications of p62/SQSTM1 in Health and Disease
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang +8 more
wiley +1 more source
Glutamine Metabolism in Health and Diseases
Glutamine metabolism acts as a metabolic hub connecting cellular stress adaptation, immune regulation, and disease development. Through regulating energy production, biosynthesis, redox balance, and nitrogen metabolism, glutamine supports cellular homeostasis under physiological and pathological conditions.
Yi Ding +3 more
wiley +1 more source
Regulatory NLRs in HSV-1 Infection: Direct Evidence, Comparative Mechanisms and Testable Hypotheses. [PDF]
Zhu M +9 more
europepmc +1 more source
Emerging Paediatric Uses of Dupilumab Beyond Approvals
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese +11 more
wiley +1 more source
Diagnosis of Mucocutaneous Herpetic Infections by PCR without DNA Extraction [PDF]
Mauricio L Nogueira +5 more
doaj +1 more source
Early HHV-6 IgG and IgA responses during acute SARS-CoV-2 infection in relation to long COVID: a multicohort observational study. [PDF]
Choudhury A +14 more
europepmc +1 more source

