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Characteristics of live bovine herpesvirus-1 vaccines

The Veterinary Journal, 2005
The common disease caused by bovine herpes virus 1 infection is febrile rhinotracheitis (FRT) and under certain conditions the virus is strongly implicated in pre-disposing cattle to pneumonic pasteurellosis. These illnesses account for a significant economic loss in the cattle industry worldwide and vaccination is widely applied.
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Detection of bovine herpesvirus-1 in bovine semen by a nested PCR assay

Journal of Virological Methods, 1993
A nested PCR assay targeting a portion of the glycoprotein IV gene has been developed for the detection of Bovine Herpesvirus-1 (BHV-1). Rapid and sensitive detection of the PCR products was achieved using a nonisotopic reverse dot-blot format with a visible color readout. Cross-reactivity of this PCR assay was not observed with the closely related BHV-
M, Wiedmann   +4 more
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Effects of immunization with bovine herpesvirus-1 glycoproteins on bovine herpesvirus-1-induced alteration of bovine neutrophil chemotactic and anti-Pasteurella haemolytica activities

Vaccine, 1988
It has been reported previously that active bovine herpesvirus-1 (BHV-1) infection greatly enhances the susceptibility of cattle to secondary bacterial pneumonia involving Pasteurella haemolytica. The present study examines the possibility that immunization of BHV-1 naive calves with purified BHV-1 glycoproteins would protect them against changes in ...
E J, Noel   +3 more
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Modified Bovine Herpesvirus 1 for Protein Secretion

2009
The traditional way to utilize bovine herpesvirus 1 (BHV-1) and many other herpesviruses as vectors for synthesis of heterologous proteins like reporter proteins, antigens, or immunomodulatory active molecules was (and still is) the expression of the protein of interest from an entire gene consisting of promoter, 5'- and 3'-noncoding regions, the open ...
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Prevalence of bovine herpesvirus-1 in the Belgian cattle population

Preventive Veterinary Medicine, 2000
The national bovine herpesvirus 1 (BHV-1) seroprevalence (apparent prevalence) in the Belgian cattle population was determined by a serological survey that was conducted from December 1997 to March 1998. In a random sample of herds (N=556), all cattle (N=28478) were tested for the presence of antibodies to glycoprotein B of BHV-1.
Boelaert, F.   +9 more
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Effect of genistein on replication of bovine herpesvirus type 1

American Journal of Veterinary Research, 2002
Abstract Objective—To study the antiviral activity of genistein, a soya isoflavone, on in vitro replication of bovine herpesvirus type 1 (BHV-1). Sample Population—Madin-Darby bovine kidney (MDBK) cells. Procedure—Effects of genistein on the magnitude and kinetics of inhibition of BHV-1 phosphorylation of glycoprotein E ...
Shaw M, Akula   +4 more
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Temporal control of bovine herpesvirus 1 glycoprotein synthesis

Journal of Virology, 1987
The gI, gIII, and gIV glycoproteins are major bovine herpesvirus 1 antigens involved in virus neutralization. Results indicate that the gI and gIV glycoproteins were expressed as beta proteins, whereas the gIII glycoprotein was expressed strictly as a gamma protein. These findings suggest that gI and gIV may be superior to gIII as vaccine candidates.
G V, Ludwig, G J, Letchworth
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Bovine Herpesvirus 1 (Bhv-1(: Biology, Pathogenesis, and Control

1995
Publisher Summary The past decade has seen very significant progress in the identification and characterization of the proteins of vovine herpesvirus 1 (BHV-1), and in understanding their role in the initiation of infection at the receptor level and in virus replication.
S K, Tikoo, M, Campos, L A, Babiuk
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Detection of the bovine herpesvirus-1 (BHV-1) genome by PCR

Journal of Virological Methods, 1993
The amplification of the 468 bp fragment of the BHV-1 genome by PCR is described. The 22 bp oligomers from the BHV-1 gI gene were used as primers. For successful amplification the thermal denaturation (100 degrees C/8 min, ice) of the DNA sample was carried out prior to the cycling (95 degrees C for 1 min, 56 degrees C for 1 min, 73 degrees C for 1 min)
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