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Comprehensive Analysis of Equid Herpesvirus Recombination: An Insight Into the Repeat Regions [PDF]

open access: yesJournal of Equine Veterinary Science, 2023
High-throughput sequencing of genomes has expanded our knowledge of the Alphaherpesvirinae, a widely extended subfamily of DNA viruses that recombine to increase their genetic diversity. It has been acknowledged that Equid herpesvirus 1 (EHV-1) and equid
Rocio Lucia Tau, Sonia Alejandra Romera
exaly   +2 more sources
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Virulence of the V592 Isolate of Equid Herpesvirus-1 in Ponies

Journal of Comparative Pathology, 2000
The V592 strain of equid herpesvirus-1 (EHV-1), which was originally isolated from a fetus during an abortion epizootic, has proved to be of low virulence in infection studies. Five Welsh Mountain pony mares and one foal were challenged intranasally or by aerosol with this isolate, and monitored clinically and virologically.
K C, Smith   +5 more
openaire   +2 more sources

Skin Hypersensitivity to Equid Herpesvirus Type 1 in Horses

Zentralblatt für Veterinärmedizin Reihe B, 2010
Summary Ten mares naturally infected with equid herpesvirus 1 (EHV-1) were intradermally injected with an antigen prepared from livers of EHV-1 infected hamsters. All mares showed strong cutaneous reactions. The reactions at the site of injection of the control antigen were very small.
T, Frymus   +3 more
openaire   +2 more sources

In vitro stimulation of foal lymphocytes with equid herpesvirus 1

Research in Veterinary Science, 1977
The RAC-H strain of equid herpesvirus I (EHV-1) replicated in gnotobiotic foal leucocytes in vitro only when they were first stimulated with phytohaemagglutinin (PHA). Virus inactivated by heat or ultraviolet (L'V) light induced considerable stimulation of sensitised lymphocytes (LS), either purified or in whole leucocyte cultures, while live virus did
G R, Thomson, J A, Mumford
openaire   +2 more sources

Cross-hybridization of equid herpesvirus-2 (EHV-2) and herpes simplex virus-1 (HSV-1) genes to equid herpesvirus-1 (EHV-1)

Veterinary Microbiology, 1993
In contrast to previous findings, the Ab4 isolate of equid herpesvirus-1 (EHV-1) was shown to share homology with the G9 isolate of equid herpesvirus-2 (EHV-2). Using Southern blotting and stringent hybridization conditions, a significant proportion of this cross-hybridization was identified by the immediate-early gene-3 (IE-3) probe from herpes ...
A S, Purewal   +4 more
openaire   +2 more sources

Equine Interferons Following Exposure to Equid Herpesvirus-1 or -4

Journal of Interferon Research, 1989
When 23 ponies were infected with equid herpesvirus-1 or -4 (EHV-1 or EHV-4), nasal shedding of interferon (IFN) correlated closely with the duration of viral excretion. Equine interferon (EqIFN) was detected in the serum only from animals infected with the EHV-1 virus, and here high levels correlated with clinical symptoms of locomotor disorder and ...
N, Edington, C G, Bridges, L, Griffiths
openaire   +2 more sources

In vitro neutralization of equid herpesvirus 1 mediated by recombinant antibodies

Journal of Immunological Methods, 2008
A phage antibody display library of single chain fragment variables (scFv) was applied to develop anti-equid herpesvirus-1 (EHV-1) glycoprotein D (gD) neutralizing antibodies. To enrich for specific scFvs, the phage antibody library was panned against epitope derived from the N-terminal part of EHV-1 gD.
D, Molinková, P, Skládal, V, Celer
openaire   +2 more sources

Virological and serological investigation of Equid herpesvirus 1 infection in New Zealand

Veterinary Microbiology, 2015
Infection with equid herpesvirus 1 (EHV-1) may be asymptomatic, or may result in respiratory disease, abortion, neonatal death, or neurological disease. The aim of this study was to estimate the prevalence of EHV-1 infection, including differentiation between genotypes with aspartic acid (D) and asparagine (N) at position 752 of the DNA polymerase ...
M Dunowska   +2 more
exaly   +3 more sources

Experimental reactivation of equid herpesvirus 1 (EHV 1) following the administration of corticosteroids

Equine Veterinary Journal, 1985
Summary Eight ponies were experimentally infected with equid herpesvirus 1 (EHV 1) (subtype 1). All animals showed clinical and serological evidence of infection and virus was isolated from nasal swabs and leucocytes. These ponies were kept in isolation for a further three months during which time complement fixing antibody decreased ...
N, Edington, C G, Bridges, A, Huckle
openaire   +2 more sources

Trials of an inactivated equid herpesvirus 1 vaccine: challenge with a subtype 1 virus

Veterinary Record, 1984
Vaccinated yearlings , two-year-old and in-foal pony mares with appropriate controls were exposed to aerosols of a subtype 1 virus one to two months after two or three vaccinations; all became infected. No obvious differences in the febrile responses, clinical signs and subsequent abortions were found between vaccinated and control mares.
R, Burrows, D, Goodridge, M S, Denyer
openaire   +2 more sources

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