Results 111 to 120 of about 1,856,095 (286)
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Signaling by Human Herpesvirus 8 kaposin A through Direct Membrane Recruitment of cytohesin-1 [PDF]
The induction of a transformed cellular phenotype by viruses requires the modulation of signaling pathways through viral proteins. We show here that the phenotypic changes induced by the kaposin A protein of human herpesvirus 8 are mediated through its direct interaction with cytohesin-1, a guanine nucleotide exchange factor for ARF GTPases and ...
Wolfgang Nagel+8 more
openaire +2 more sources
Background: Human herpesvirus is a large enveloped DNA virus and significant human pathogen. Many studies examined oral squamous cell carcinoma for herpes simplex virus and suggested an association with this virus; others have demonstrated human ...
Najwa Ahmed Mohammed+2 more
doaj +2 more sources
The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution.
The complete DNA sequence was determined for strain U1102 of human herpesvirus-6, a CD4+ T-lymphotropic virus with disease associations in immunodeficient settings and a possible complicating factor in AIDS.
U. Gompels+11 more
semanticscholar +1 more source
Background G-quadruplexes regulate gene expression, recombination, packaging and latency in herpesviruses. Herpesvirus-encoded miRNAs have been linked to important biological functions. The presence and the biological role of G-quadruplexes have not been
Shivani Kumar+4 more
doaj +1 more source
Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. [PDF]
Herpesviruses are enveloped viruses that are prevalent in the human population and are responsible for diverse pathologies, including cold sores, birth defects and cancers.
Bi, Guo-Qiang+4 more
core
Human Exposure to Herpesvirus B–Seropositive Macaques, Bali, Indonesia
Herpesvirus B (Cercopithecine herpesvirus 1) has been implicated as the cause of approximately 40 cases of meningoencephalitis affecting persons in direct or indirect contact with laboratory macaques. However, the threat of herpesvirus B in nonlaboratory
G. Engel+6 more
semanticscholar +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
Dermatology continues to develop at a steady pace. In the past few years there have been exciting advances in our understanding of skin structure and function in health and disease and progress in genetics, epidemiology, immunology, pharmacology and ...
Boffa, Michael J.
core +1 more source
Several studies have suggested an association between human herpesvirus 6 (HHV-6) and multiple sclerosis (MS). We have previously studied intrathecal production of antibody to lymphotropic herpesviruses in MS patients and the presence of human ...
M. Enbom+5 more
semanticscholar +1 more source