Mouse Models for Human Herpesviruses
Pathogens, 2023 More than one hundred herpesviruses have been isolated from different species so far, with nine infecting humans. Infections with herpesviruses are characterized by life-long latency and represent a significant challenge for human health.
Ivana Kutle, Anne Dittrich, Dagmar Wirth
doaj +1 more source
Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies [PDF]
The Korean Journal of Internal Medicine, 2020 Background/Aims A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been ...
Junshik Hong +10 more
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Potential effect of decreased levels of folic acid and vitamin B12 on herpes simplex virus keratitis reactivation [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Most cases of herpetic keratitis present a recurrent disease as a result of herpes simplex virus type 1 reactivation from latency in the nearest sensory ganglia.
Savić Borivoje +5 more
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Using CSF Proteomics to Investigate Herpesvirus Infections of the Central Nervous System
Viruses, 2022 Herpesviruses have complex mechanisms enabling infection of the human CNS and evasion of the immune system, allowing for indefinite latency in the host. Herpesvirus infections can cause severe complications of the central nervous system (CNS).
Saima Ahmed +8 more
doaj +1 more source
An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
, 2020 beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip +8 more
core +2 more sources
Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes [PDF]
Archives of Virology, 2018 Mitochondrial movement and distribution throughout the cytoplasm is crucial for maintaining cell homeostasis. Mitochondria are dynamic organelles but can be functionally disrupted during infection. Here, we show that the ubiquitous human pathogens HHV-1 and HHV-2 induce changes in the mitochondrial morphology and distribution in the early and late ...
Marcin Chodkowski +9 more
openaire +3 more sources
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
, 2007 Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources
Herpes Group Viruses: a Seroprevalence Study in Hemodialysis Patients
Acta Clinica Croatica, 2017 Herpes group viruses (herpes simplex virus, HSV; varicella-zoster virus, VZV; cytomegalovirus, CMV; and Epstein-Barr virus, EBV) remain an important cause of morbidity in immunocompromised persons.
Tatjana Vilibić-Čavlek +4 more
doaj +1 more source
Multiple human herpesvirus-8 infection [PDF]
, 2003 In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM +7 more
core +1 more source
Induction of Human Immunodeficiency Virus 1 Replication by Human Herpesvirus 8
Archives of Pathology & Laboratory Medicine, 2001 Abstract Background.—Human immunodeficiency virus 1 (HIV-1)–infected individuals are commonly infected with herpesviruses, including cytomegalovirus, herpes simplex virus, varicella-zoster virus, and human herpesvirus 8 (HHV-8, also known as Kaposi sarcoma–associated herpesvirus [KSHV]).
Brian J. Nickoloff +3 more
openaire +3 more sources