Using CSF Proteomics to Investigate Herpesvirus Infections of the Central Nervous System
Viruses, 2022 Herpesviruses have complex mechanisms enabling infection of the human CNS and evasion of the immune system, allowing for indefinite latency in the host. Herpesvirus infections can cause severe complications of the central nervous system (CNS).
Saima Ahmed +8 more
doaj +1 more source
Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes [PDF]
Archives of Virology, 2018 Mitochondrial movement and distribution throughout the cytoplasm is crucial for maintaining cell homeostasis. Mitochondria are dynamic organelles but can be functionally disrupted during infection. Here, we show that the ubiquitous human pathogens HHV-1 and HHV-2 induce changes in the mitochondrial morphology and distribution in the early and late ...
Marcin Chodkowski +9 more
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Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A [PDF]
, 2019 Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis.
Boyd, Joseph R. +12 more
core +1 more source
Herpes Group Viruses: a Seroprevalence Study in Hemodialysis Patients
Acta Clinica Croatica, 2017 Herpes group viruses (herpes simplex virus, HSV; varicella-zoster virus, VZV; cytomegalovirus, CMV; and Epstein-Barr virus, EBV) remain an important cause of morbidity in immunocompromised persons.
Tatjana Vilibić-Čavlek +4 more
doaj +1 more source
A murine herpesvirus closely related to ubiquitous human herpesviruses causes T-cell depletion [PDF]
, 2017 The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these viruses have been implicated in many
Beatrice Plougastel-Douglas +11 more
core +2 more sources
Global Diversity within and between Human Herpesvirus 1 and 2 Glycoproteins [PDF]
Journal of Virology, 2015 ABSTRACT Human herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are large-genome DNA viruses that establish a persistent infection in sensory neurons and commonly manifest with recurring oral or genital erosions that transmit virus. HSV encodes 12 predicted glycoproteins that serve various functions, including cellular attachment, entry, and ...
Aaron A. R. Tobian +9 more
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Induction of Human Immunodeficiency Virus 1 Replication by Human Herpesvirus 8
Archives of Pathology & Laboratory Medicine, 2001 Abstract Background.—Human immunodeficiency virus 1 (HIV-1)–infected individuals are commonly infected with herpesviruses, including cytomegalovirus, herpes simplex virus, varicella-zoster virus, and human herpesvirus 8 (HHV-8, also known as Kaposi sarcoma–associated herpesvirus [KSHV]).
Brian J. Nickoloff +3 more
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Persistent infection of a human lymphoblastoid cell line with equine herpesvirus 1 [PDF]
Infection and Immunity, 1979 Infection of a human lymphoblastoid cell line (Jijoye line derived from a Burkitt lymphoma which contains Epstein-Barr virus) with equine herpesvirus 1, maintained and observed for 53 days, was characterized by the continuous production of infectious extracellular and intracellular virus.
P. M. Feorino +2 more
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Speculations on the clinical significance of asymptomatic viral infections [PDF]
, 2016 A detailed understanding of asymptomatic chronic viral infections is critical to analyse their pathogenesis, assess the severity and burden of disease and, where required, optimize public health control measures.
Gentile, Giuseppe, Micozzi, Alessandra
core +1 more source
Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]
, 2007 Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core +4 more sources