Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes [PDF]
Mitochondrial movement and distribution throughout the cytoplasm is crucial for maintaining cell homeostasis. Mitochondria are dynamic organelles but can be functionally disrupted during infection. Here, we show that the ubiquitous human pathogens HHV-1 and HHV-2 induce changes in the mitochondrial morphology and distribution in the early and late ...
Marcin Chodkowski +9 more
openaire +3 more sources
Seroprevalence of Kaposi sarcoma-associated herpesvirus and other serologic markers in the Brazilian Amazon. [PDF]
To determine the presence of Kaposi sarcoma-associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Mascheretti, Melissa +27 more
core +1 more source
Global Diversity within and between Human Herpesvirus 1 and 2 Glycoproteins [PDF]
ABSTRACT Human herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are large-genome DNA viruses that establish a persistent infection in sensory neurons and commonly manifest with recurring oral or genital erosions that transmit virus. HSV encodes 12 predicted glycoproteins that serve various functions, including cellular attachment, entry, and ...
Susanna L, Lamers +9 more
openaire +2 more sources
Persistent infection of a human lymphoblastoid cell line with equine herpesvirus 1 [PDF]
Infection of a human lymphoblastoid cell line (Jijoye line derived from a Burkitt lymphoma which contains Epstein-Barr virus) with equine herpesvirus 1, maintained and observed for 53 days, was characterized by the continuous production of infectious extracellular and intracellular virus.
L F, Roumillat +2 more
openaire +2 more sources
Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast
Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann +3 more
wiley +1 more source
Analysis of the human herpesvirus-6 immediate-early 1 protein
Herpesvirus immediate-early (IE) gene products play key roles in establishing productive infections, regulating reactivation from latency and evading immune recognition. Analyses of HHV-6 IE gene expression have revealed that the IE1 gene of the HHV-6A and HHV-6B variants exhibits a higher degree of sequence variation than other regions of the genome ...
Richard, Stanton +4 more
openaire +2 more sources
Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
Sitas, F. +29 more
core +2 more sources
Background: Viral infections in pregnancy are major causes of maternal and fetal morbidity and mortality. Infections develop in the neonate transplacentally, perinatally or postnatally.
Areej A. Hussein +2 more
doaj +6 more sources
Human Herpesvirus 8 Reactivation and Human Immunodeficiency Virus Type 1 gp120
Abstract Context.—Human herpesvirus 8 (HHV-8) is the presumed etiologic agent of Kaposi sarcoma (KS), the most common neoplasm in patients with acquired immunodeficiency syndrome. Current evidence indicates HHV-8 is necessary, but not sufficient, for KS development without the involvement of other cofactors.
Chun, Lu +4 more
openaire +2 more sources
Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis [PDF]
Kaposi's sarcoma herpesvirus (KSHV) encodes a cluster of twelve micro (mi)RNAs, which are abundantly expressed during both latent and lytic infection.
Contrant, M +60 more
core +1 more source

