Results 1 to 10 of about 911 (75)

The First Record of an Aggressive Form of Ocular Tumour Enhanced by Marek’s Disease Virus Infection in Layer Flock in Al-Najaf, Iraq [PDF]

Veterinary Medicine International
Marek’s disease (MD) is a highly infectious poultry illness with a tendency to form tumours in peripheral nerves and internal organs of affected birds. Tumours accompany MD, mostly caused by oncogenic Gallid alpha herpesvirus 2 (MD Herpes virus serotype ...
Aoula Al-Zebeeby, Ali Hadi Abbas, Haider Abas Alsaegh, Furkan Sabbar Alaraji   +3 more
doaj   +3 more sources

Structural Insights Into the Nuclear Import of Gallid Alphaherpesvirus 1 Large Tegument Protein. [PDF]

Microbiologyopen
The study identifies and characterizes a bipartite nuclear localization signal within the GaAHV‐1 UL36 large tegument protein, revealing its structural interaction with importin α/β1 and confirming a conserved mechanism of nuclear import through biochemical, crystallographic, and mutational analyses.
Nath BK, Swarbrick CMD, Blades R, Ariawan D, Tietz O, Alvisi G, Forwood JK, Sarker S.   +7 more
europepmc   +2 more sources

Pathology and Molecular Diagnosis of Marek's Disease Virus in Chickens in Nigeria. [PDF]

Scientifica (Cairo)
Marek’s disease caused by Marek’s disease virus (MDV) serotype 1 is an economically important neoplastic disease of poultry. Diagnosis of this disease is usually based on clinical signs, postmortem lesions, and diagnostic tests like cytology, histopathology, and molecular‐based methods.
Fagbohun OA, Oluladun AC, Jarikre TA, Alaka OO, Oyagbemi AA, Adesina RD, Esan OO, Akinniyi OO, Adetona MO, Omobowale TO, Mamoh UJ, Jaja IF.   +11 more
europepmc   +2 more sources

The Requirement of Turkey Herpesvirus (HVT) Glycoprotein C During Natural Infection in Chickens and Turkeys [PDF]

Pathogens
The glycoprotein C (gC) of gallid alphaherpesvirus 2—better known as Marek’s disease (MD) virus (MDV)—and gallid alphaherpesvirus 3 is required for horizontal transmission in chickens.
Huai Xu, Widaliz Vega-Rodriguez, Kathrine Van Etten, Keith Jarosinski   +3 more
doaj   +2 more sources

Rapid taxonomic categorization of short, abundant virus sequences for ecological analyses. [PDF]

Ecol Evol
We sampled 1086 bats from two, adjacent Puerto Rican caves and tested them for infection by herpesviruses, resulting in 3131 short, viral sequences. Using percent identity of nucleotides and a machine learning algorithm (affinity propagation), we categorized herpesviruses into 43 operational taxonomic units (OTUs).
Sjodin AR, Willig MR, Rodríguez-Durán A, Anthony SJ.   +3 more
europepmc   +2 more sources

mRNA Splicing of UL44 and Secretion of Alphaherpesvirinae Glycoprotein C (gC) Is Conserved among the Mardiviruses [PDF]

Viruses
Marek’s disease (MD), caused by gallid alphaherpesvirus 2 (GaAHV2) or Marek’s disease herpesvirus (MDV), is a devastating disease in chickens characterized by the development of lymphomas throughout the body.
Huai Xu, Widaliz Vega-Rodriguez, Valeria Campos, Keith W. Jarosinski   +3 more
doaj   +2 more sources

Investigation of a herpesvirus outbreak in mixed breeds of adult domestic ducks using next generation sequencing. [PDF]

PLoS ONE, 2023
This report characterizes the first lethal outbreak of Marek's disease on a large farm of mixed-breed adult ducks (>18,000) and identifies the pathogen that resulted in high mortality (35%).
Hassan Abu Damir, Waqar Ahmad, Neena G Panicker, Layla I Mohamed, Elhag A Omer, Jörg Kinne, Ulrich Wernery, Abdu Adem, Mahmoud A Ali, Farah Mustafa   +9 more
doaj   +2 more sources

The Requirement of Glycoprotein C for Interindividual Spread Is Functionally Conserved within the Alphaherpesvirus Genus (Mardivirus), but Not the Host (Gallid)

Viruses, 2021
Marek’s disease (MD) in chickens is caused by Gallid alphaherpesvirus 2, better known as MD herpesvirus (MDV). Current vaccines do not block interindividual spread from chicken-to-chicken, therefore, understanding MDV interindividual spread provides ...
Widaliz Vega-Rodriguez, Nagendraprabhu Ponnuraj, Maricarmen Garcia, Keith W. Jarosinski   +3 more
doaj   +1 more source

Genetic evolution of Marek's disease virus in vaccinated poultry farms [PDF]

Veterinary World, 2021
Background and Aim: The Marek's disease virus (MDV) is a neoplastic disease causing serious economic losses in poultry production. This study aimed to investigate MDV occurrence in poultry flocks in the Lower Egypt during the 2020 breakout and ...
Nahed Yehia, Hemat S. El-Sayed, Sabry E. Omar, Ahmed Erfan, Fatma Amer   +4 more
doaj   +1 more source

U_S3 Serine/Threonine Protein Kinase from MDV-1, MDV-2, and HVT Differentially Regulate Viral Gene Expression and Replication

Microorganisms, 2021
Gallid alphaherpesvirus 2 (GaHV-2), commonly known as Marek’s disease virus type 1 (MDV-1), is an oncogenic avian alphaherpesvirus, and along with its close relatives—Gallid alphaherpesvirus 3 (GaHV-3) or MDV-2 and Meleagrid alphaherpesvirus 1 (MeHV-1 ...
Yifei Liao, Xin Fang, Mohammad AI-Mahmood, Qinglei Li, Blanca Lupiani, Sanjay M. Reddy   +5 more
doaj   +1 more source