The Transcriptional Landscape of Marek’s Disease Virus in Primary Chicken B Cells Reveals Novel Splice Variants and Genes [PDF]
, 2019 Marek’s disease virus (MDV) is an oncogenic alphaherpesvirus that infects chickens and poses a serious threat to poultry health. In infected animals, MDV efficiently replicates in B cells in various lymphoid organs.
Bertzbach, Luca D. +7 more
core +2 more sources
Viral Bacterial Artificial Chromosomes: Generation, Mutagenesis, and Removal of Mini‐F Sequences
BioMed Research International, Volume 2012, Issue 1, 2012., 2012 Maintenance and manipulation of large DNA and RNA virus genomes had presented an obstacle for virological research. BAC vectors provided a solution to both problems as they can harbor large DNA sequences and can efficiently be modified using well‐established mutagenesis techniques in Escherichia coli.
B. Karsten Tischer +2 more
wiley +1 more source
Novel genetic factors in Marek’s disease virus pathogenesis and establishment of a cell culture-based viral integration system [PDF]
, 2022 Marek’s disease virus (MDV) is a highly contagious alphaherpesvirus that causes neurological disorders, immunosuppression, and deadly lymphomas in chickens.
You, Yu
core +1 more source
Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes
, 2008 By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin +20 more
core +1 more source
Longitudinal survey of microbiome associated with particulate matter in a megacity. [PDF]
, 2020 BackgroundWhile the physical and chemical properties of airborne particulate matter (PM) have been extensively studied, their associated microbiome remains largely unexplored.
Gilbert, Jack A +12 more
core +1 more source
Mixed infection by fowlpox virus and Chlamydophila psittaci in a commercial laying hen flock [PDF]
, 2013 An outbreak of fowlpox occurred in a commercial laying hen flock in one of the western provinces of Poland. Clinical signs suggested fowlpox and the diagnosis was confirmed by histopathological detection of Bollinger bodies within the epithelial cells ...
Jasik, Agnieszka +5 more
core +1 more source
BMC Genomics, 2012 Background Infectious laryngotracheitis virus (ILTV; gallid herpesvirus 1) infection causes high mortality and huge economic losses in the poultry industry. To protect chickens against ILTV infection, chicken-embryo origin (CEO) and tissue-culture origin
Lee Jeongyoon +2 more
doaj +1 more source
Characterization of duck enteritis virus UL53 gene and glycoprotein K [PDF]
, 2011 Background Most of the previous research work had focused on the epidemiology and prevention of duck enteritis virus (DEV). Whilst with the development of protocols in molecular biology, nowadays more and more information about the genes of ...
Shunchuan Zhang +10 more
core +1 more source
The Modulation of Apoptotic Pathways by Gammaherpesviruses [PDF]
, 2016 Apoptosis or programmed cell death is a tightly regulated process fundamental for cellular development and elimination of damaged or infected cells during the maintenance of cellular homeostasis. It is also an important cellular defense mechanism against
Prerna Dabral +4 more
core +3 more sources
A common live-attenuated avian herpesvirus vaccine expresses a very potent oncogene [PDF]
, 2019 Vaccines play a crucial role in the protection of animals and humans from deadly pathogens. The first vaccine that also protected against cancer was developed against the highly oncogenic herpesvirus Marek’s disease virus (MDV).
Bertzbach, Luca D. +2 more
core +1 more source