Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects [PDF]
Memorias do Instituto Oswaldo Cruz, 2018 BACKGROUND Human herpesvirus 2 (HHV-2) have DNA genome with a limited genetic variability and have been classified into two clades. OBJECTIVES To identify and characterise six HHV-2 isolates derived from Brazilian women.
Lyana Rodrigues Pinto Lima +5 more
doaj +4 more sources
Human Herpesvirus 8 infection may contribute to oxidative stress in diabetes type 2 patients [PDF]
BMC Research Notes, 2020 Objective To investigate the link between Human Herpesvirus 8 (HHV8) infection and plasma oxidative stress in patients with diabetes mellitus type 2 (DM2).
Alessandra Incani +6 more
doaj +4 more sources
Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes [PDF]
Archives of Virology, 2018 Mitochondrial movement and distribution throughout the cytoplasm is crucial for maintaining cell homeostasis. Mitochondria are dynamic organelles but can be functionally disrupted during infection. Here, we show that the ubiquitous human pathogens HHV-1 and HHV-2 induce changes in the mitochondrial morphology and distribution in the early and late ...
Marcin Chodkowski +9 more
openaire +3 more sources
Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene [PDF]
Journal of Virology, 1997 Here we demonstrate that open reading frame 16 (ORF16) of the oncogenic herpesvirus saimiri protects cells from heterologous virus-induced apoptosis. The BH1 and BH2 homology domains are highly conserved in ORF16, and ORF16 heterodimerizes with Bcl-2 family members Bax and Bak. However, ORF16 lacks the core sequence of the conserved BH3 homology domain,
Rollie J. Clem +6 more
openaire +3 more sources
Global Diversity within and between Human Herpesvirus 1 and 2 Glycoproteins [PDF]
Journal of Virology, 2015 ABSTRACT Human herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are large-genome DNA viruses that establish a persistent infection in sensory neurons and commonly manifest with recurring oral or genital erosions that transmit virus. HSV encodes 12 predicted glycoproteins that serve various functions, including cellular attachment, entry, and ...
Aaron A. R. Tobian +9 more
openaire +2 more sources
Complete genome sequence and taxonomic position of anguillid herpesvirus 1 [PDF]
, 2010 Eel herpesvirus or anguillid herpesvirus 1 (AngHV1) frequently causes disease in freshwater eels. The complete genome sequence of AngHV1 and its taxonomic position within the family Alloherpesviridae were determined. Shotgun sequencing revealed a 249 kbp
Abma-Henkens, M.H.C. +8 more
core +11 more sources
An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
, 2020 beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip +8 more
core +2 more sources
Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
, 2012 Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Amy B. Pedersen +12 more
core +1 more source
Review part 2: Human herpesvirus‐6 in central nervous system diseases [PDF]
Journal of Medical Virology, 2010 AbstractJ. Med. Virol. 82:1669–1678, 2010. © 2010 Wiley‐Liss, Inc.
Yao, Karen +4 more
openaire +4 more sources
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]
, 2016 Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan +17 more
core +2 more sources