Results 11 to 20 of about 101,863,695 (246)

Novel γ-2-Herpesvirus of the Rhadinovirus 2 Lineage in Gibbons

Emerging Infectious Diseases, 2004
We obtained 475 nucleotides of the DNA polymerase gene of a novel human herpesvirus 8 homolog sequence in a gibbon. The finding of this new gibbon virus, which clusters with a related chimpanzee virus in the rhadinovirus 2 genogroup, suggests the ...
Renan Duprez, Emmanuelle Boulanger, Yannick Roman, Antoine Gessain   +3 more
doaj   +2 more sources

Using CSF Proteomics to Investigate Herpesvirus Infections of the Central Nervous System

Viruses, 2022
Herpesviruses have complex mechanisms enabling infection of the human CNS and evasion of the immune system, allowing for indefinite latency in the host. Herpesvirus infections can cause severe complications of the central nervous system (CNS).
Saima Ahmed, Patrick van Zalm, Emily A. Rudmann, Michael Leone, Kiana Keller, John A. Branda, Judith Steen, Shibani S. Mukerji, Hanno Steen   +8 more
doaj   +2 more sources

Novel variants of human herpesvirus 2 from Brazilian HIV-1 coinfected subjects [PDF]

Memorias do Instituto Oswaldo Cruz, 2018
BACKGROUND Human herpesvirus 2 (HHV-2) have DNA genome with a limited genetic variability and have been classified into two clades. OBJECTIVES To identify and characterise six HHV-2 isolates derived from Brazilian women.
Lyana Rodrigues Pinto Lima, Nathália Alves de Araújo, Alexandro Guterres, José Henrique Pilotto, Christian Niel, Vanessa Salete de Paula   +5 more
doaj   +3 more sources

Human Herpesvirus 8 infection may contribute to oxidative stress in diabetes type 2 patients [PDF]

BMC Research Notes, 2020
Objective To investigate the link between Human Herpesvirus 8 (HHV8) infection and plasma oxidative stress in patients with diabetes mellitus type 2 (DM2).
Alessandra Incani, Luisa Marras, Gabriele Serreli, Angela Ingianni, Raffaello Pompei, Monica Deiana, Fabrizio Angius   +6 more
doaj   +4 more sources

Herpesvirus and Adenotonsillar Hypertrophy in Chinese Children: An Epidemiological and Clinical Analysis. [PDF]

World J Otorhinolaryngol Head Neck Surg
ABSTRACT Objective To investigate the possible association between adenotonsillar hypertrophy (ATH) and herpesviral infections in children, and to examine correlations between specific viral detection and clinical characteristics. Methods We enrolled 43 children aged 3–14 years with ATH (mean age 76.56 ± 25.65 months; 31 boys).
Ji TT, Fan M, Yu D, Ni X, Li XD, Wang XY, Lu L, Su W, Tang LX, Zhang W, Xiao X, Han Y, Mei L, Wang SC.   +13 more
europepmc   +2 more sources

Multiple Sclerosis and Viruses: « Liaisons Dangereuses ». [PDF]

Rev Med Virol
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Plavina S, Malakovska D, Kalnina J, Trapina I, Leonova E, Habib M, Schifmann S, Paramonovs J, Sjakste N, Vassetzky Y, Drouet E, Paramonova N.   +11 more
europepmc   +2 more sources

Human herpesvirus type 1 and type 2 disrupt mitochondrial dynamics in human keratinocytes [PDF]

Archives of Virology, 2018
Mitochondrial movement and distribution throughout the cytoplasm is crucial for maintaining cell homeostasis. Mitochondria are dynamic organelles but can be functionally disrupted during infection. Here, we show that the ubiquitous human pathogens HHV-1 and HHV-2 induce changes in the mitochondrial morphology and distribution in the early and late ...
Marcin Chodkowski, Izabela Serafińska, Joanna Brzezicka, Anna Golke, Anna Słońska, Małgorzata Krzyżowska, Piotr Orłowski, Piotr Bąska, Marcin W. Bańbura, Joanna Cymerys   +9 more
openaire   +3 more sources

Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogene [PDF]

Journal of Virology, 1997
Here we demonstrate that open reading frame 16 (ORF16) of the oncogenic herpesvirus saimiri protects cells from heterologous virus-induced apoptosis. The BH1 and BH2 homology domains are highly conserved in ORF16, and ORF16 heterodimerizes with Bcl-2 family members Bax and Bak. However, ORF16 lacks the core sequence of the conserved BH3 homology domain,
V E, Nava, E H, Cheng, M, Veliuona, S, Zou, R J, Clem, M L, Mayer, J M, Hardwick   +6 more
openaire   +2 more sources

Global Diversity within and between Human Herpesvirus 1 and 2 Glycoproteins [PDF]

Journal of Virology, 2015
ABSTRACT Human herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are large-genome DNA viruses that establish a persistent infection in sensory neurons and commonly manifest with recurring oral or genital erosions that transmit virus. HSV encodes 12 predicted glycoproteins that serve various functions, including cellular attachment, entry, and ...
Susanna L, Lamers, Ruchi M, Newman, Oliver, Laeyendecker, Aaron A R, Tobian, Robert C, Colgrove, Stuart C, Ray, David M, Koelle, Jeffrey, Cohen, David M, Knipe, Thomas C, Quinn   +9 more
openaire   +2 more sources

Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]

, 2015
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA, Breuer, J, Gompels, UA, Tweedy, J, Depledge, D, Donaldson, CD   +5 more
core   +1 more source