Interleukin-31 new biomarker of infectious skin diseases
Introduction. The introduction of antiretroviral therapy has significantly improved the long-term prognosis of AIDS patients, but opportunistic infections can still be life-threatening for this population.
Diana Dorosh
doaj +1 more source
Tetranucleotide Profile of Herpesvirus DNA
Introduction. Herpesvirus DNAs (about 90% of the total genomic sequences of the Herpesvirales family presented in GenBank) contain at a minimum concentration one of the two tetranucleotides, CTAG or TCGA.
Felix P. Filatov, Alexander V. Shargunov
doaj +1 more source
Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews +14 more
core +1 more source
CNS Complications of Primary Human Herpesvirus-6 Infection
Central nervous system manifestations of primary human herpesvirus-6 (HHV-6) are described in 9 children, ages 3 to 24 months, with HHV-6 DNA in the cerebrospinal fluid, in a prospective study at the University of Helsinki, and other centers in Finland.
J Gordon Millichap
doaj +1 more source
Glass eels and viruses – a lesson learnt from stocking the eastern German Baltic Sea coast
Abstract Concerns about Anguillid herpesvirus 1 (AngHV‐1) in European eels, especially due to stocking measures, is increasingly coming into focus and raises questions regarding disease monitoring and prevention. In the past, stocking of AngHV‐1‐positive eels into waters assumed AngHV‐1‐free has led to a rapid increase of infected eels in the wild. For
Laura Kullmann +3 more
wiley +1 more source
The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael +9 more
core +1 more source
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin [PDF]
Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu ...
Wilson, Sam J. +48 more
core +1 more source
Herpesvirus-6 Infection and Febrile Seizures
Human herpesvirus-6 (HHV-6) infection, incidence, course, complications, and its potential for persistence or reactivation, was studied in infants and children under 3 years of age seen in the ER over a three-year period at the University of Rochester ...
J Gordon Millichap
doaj +1 more source
Herpesvirus lytic infection-induced mitophagy via viral interferon regulatory factor 1
Viral control of mitochondria via mitophagy has a dampening effect on mitochondrion-mediated innate immune responses. We previously found that human herpesvirus 8 (HHV-8) could activate mitophagy via its lytic gene product vIRF-1 (viral interferon ...
Mai Tram Vo, Young Bong Choi
doaj +1 more source
Epidemiology and fitness effects of wood mouse herpesvirus in a natural host population [PDF]
Rodent gammaherpesviruses have become important models for understanding human herpesvirus diseases. In particular, interactions between murid herpesvirus 4 and Mus musculus (a non-natural host species) have been extensively studied under controlled ...
Pedersen, Amy B. +2 more
core +1 more source

