Results 161 to 170 of about 611,536 (212)

Natural antibody–complement dependent neutralization of bovine herpesvirus 4 by human serum

Microbes and Infection, 2007
In contrast to most gammaherpesviruses, Bovine herpesvirus 4 (BoHV-4) has a broad range of host species both in vitro and in vivo. Several in vitro studies demonstrated that some human cell lines are sensitive or even permissive to BoHV-4. These observations led to the hypothesis that cross-species transmission of BoHV-4 could lead to human infections.
Machiels, Bénédicte, Gillet, Laurent, Brito, Sieberth Do Nascimento, Drion, Pierre, Delforge, Cédric, Nizet, Yannick, Gianello, Pierre, Bona, Christophe, Costes, Bérénice, Markine-Goriaynoff, Nicolas, Vanderplasschen, Alain   +10 more
openaire   +2 more sources

Serological study of human herpesvirus simplex 1 and bovine herpesvirus 1, 2, and 4 in Kansas cattle

The Bovine Practitioner, 1989
A total of 589 beef cattle and 466 dairy cattle were tested for antibodies to herpes simplex virus-1 (HSV-1) and bovine herpes virus-1, 2, and 4 (BHV) using the indirect fluorescent antibody test (IFAT). In the beef cattle, prevalence of antibodies to HSV-1, BHV-1, 2, and 4 was 34.8%, 67.9%, 36.5% and 12.4% respectively, and in the dairy cattle ...
Phillips, R. M., Nassar, R. F.
openaire   +1 more source

Tim-1 and Tim-4 mediate entry of the human Kaposi’s sarcoma-associated herpesvirus and the related rhesus monkey rhadinovirus

2023
ABSTRACT Kaposi’s sarcoma-associated herpesvirus (KSHV) is a human tumor virus. It is associated with Kaposi’s sarcoma, primary effusion lymphoma, and multicentric Castleman’s disease. KSHV is known to interact with several different receptors, among them heparan sulfate proteoglycans, Eph family receptors, and integrins. We mutated the
Stefano Scribano, Sarah Schlagowski, Shanchuan Liu, Thomas Fricke, Xiaoliang Yang, Frank Neipel, Anna K. Großkopf, Bojan F. Hörnich, Marija Backovic, Armin Ensser, Alexander S. Hahn   +10 more
openaire   +1 more source

Modulation of CD4, CXCR-4, and CCR-5 Makes Human Hematopoietic Progenitor Cell Lines Infected with Human Herpesvirus-6 Susceptible to Human Immunodeficiency Virus Type 1

Journal of Hematotherapy & Stem Cell Research, 2000
Two CD34+ human hematopoietic progenitor cell (HPC) lines, KG-1 and TF-1, became susceptible to human immunodeficiency virus type 1 (HIV-1) infection in the presence of a concurrent infection by human herpesvirus-6 (HHV-6). We have analyzed the possible mechanism(s) underlying this phenomenon in light of the recent demonstration that at least two ...
M, Vignoli, G, Furlini, M C, Re, E, Ramazzotti, M, La Placa   +4 more
openaire   +2 more sources

4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as Non-Nucleoside Inhibitors of Human Cytomegalovirus and Related Herpesvirus Polymerases

Journal of Medicinal Chemistry, 2005
A novel series of 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potential antivirals against human herpesvirus infections resulting from human cytomegalovirus (HCMV), herpes simplex virus type 1 (HSV-1), and varicella-zoster virus (VZV).
Mark E, Schnute, Michele M, Cudahy, Roger J, Brideau, Fred L, Homa, Todd A, Hopkins, Mary L, Knechtel, Nancee L, Oien, Thomas W, Pitts, Roger A, Poorman, Michael W, Wathen, Janet L, Wieber   +10 more
openaire   +2 more sources

Detection and Analysis of Protein‐Protein Interactions between KU70 and BHRF1, a BCL2 viral analog within Human gamma herpesvirus 4

The FASEB Journal, 2020
The Epstein‐Barr virus, also known as human gamma herpesvirus 4 (HHV‐4), affects more than 90% of the adult human population worldwide. To prevent premature death of the host cell, HHV‐4 encodes for BHRF1, an anti‐apoptotic protein with sequence and structural similarities to other proteins involved in apoptosis such as BCL2, BAX and BAK, among others.
Sheighlah McManus, Alexander Emami, Alberto Zamora   +2 more
openaire   +1 more source

Synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamides with broad-spectrum human herpesvirus polymerase inhibition

Bioorganic & Medicinal Chemistry Letters, 2008
A versatile synthesis of 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxylate esters has been developed which has lead to the identification of a new series of non-nucleoside inhibitors of human herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.
Mark E, Schnute, Roger J, Brideau, Sarah A, Collier, Michele M, Cudahy, Todd A, Hopkins, Mary L, Knechtel, Nancee L, Oien, Robert S, Sackett, Allen, Scott, Mari L, Stephan, Michael W, Wathen, Janet L, Wieber   +11 more
openaire   +2 more sources

Activating transcription factor 4 (ATF4) is upregulated by human herpesvirus 8 infection, increases virus replication and promotes proangiogenic properties

Archives of Virology, 2011
Human herpesvirus 8 (HHV-8) triggers proangiogenic behaviour in endothelial cells by inducing monocyte chemoattractant protein 1 (MCP-1) through activation of Nuclear Factor κB (NF-κB). However, NF-κB inhibition still results in partial MCP-1 induction and consequent angiogenesis, suggesting the involvement of another transcriptional pathway.
CASELLI, Elisabetta, BENEDETTI, Sabrina, GRIGOLATO, Jessica, Caruso A., DI LUCA, Dario   +4 more
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DIAGNOSIS OF AN ALLERGIC REACTION TO ANTIBIOTICS IN AN PATIENT WITH ACTIVE HUMAN HERPESVIRUS -4, -6 TYPE INFECTION (CLINICAL CASE).

Georgian medical news, 2022
Beta-lactam antibiotics (BLAs) can provoke drug hypersensitivity reactions, particularly delayed-type reactions. This article presents a case of drug allergy with manifestations of Stevens-Johnson syndrome (SJD) in a 42-year-old man with yersiniosis and active herpesvirus -4, -6 type, who received amoxacillin with clavulanic acid. The patient underwent
S, Zubchenko, A, Havrylyuk, M, Lomikovska, I, Kril, S, Chuiko   +4 more
openaire   +1 more source