Results 171 to 180 of about 611,536 (212)
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Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library

Journal of Virological Methods, 2007
Human herpesvirus 8 (HHV-8) is associated with the development of Kaposi's sarcoma and several other human malignancies. Kaposin A protein of HHV-8 has been demonstrated as inducing tumorigenic transformation, being responsible for nuclear receptor coactivators in the transforming activity.
Cheng-Wen, Lin   +6 more
openaire   +2 more sources

Effect of IL‐12 and soluble IL‐4 receptor on the herpesvirus infection in human SCID chimeras whose Th2 cells predominate

Immunology & Cell Biology, 2004
Th2 cytokines, commonly detected in burn patients, have been shown as inhibitors for the generation of Th1 cells that are essential for the host's resistance against herpes simplex virus type 1 (HSV‐1) infection. In this study, the possibility of immunological treatment through the regulation of Th1/Th2 responses was examined in two kinds of human ...
Tatsushi, Katakura   +3 more
openaire   +2 more sources

4: Complete replication cycle and acquisition of tegument in nucleus of human herpesvirus 6A (HHV-6A) in astrocytes and in T-cells

Journal of Clinical Virology, 2006
The ultrastructural replication cycle of human herpesvirus 6A and 6B, both T-lymphotropic viruses, with tropism for the central nervous system,wascomparedbyelectronmicroscopyin the same cells, that is, in the T-lymphoblastoid cell line SupT-1 and in human astrocytes.
J. Ahlqvist   +7 more
openaire   +1 more source

Biologically significant interaction of human herpesvirus 8 viral interferon regulatory factor 4 with ubiquitin-specific protease 7

Journal of Virology
ABSTRACT Human herpesvirus 8 (HHV-8), associated with Kaposi sarcoma, primary effusion lymphoma (PEL), and multicentric Castleman disease, encodes four interferon regulatory factor homologs, vIRFs 1–4, that interact with and inhibit various mediators of host-cell defense against virus infection.
Zunlin Yang, John Nicholas
openaire   +2 more sources

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

Bioorganic & Medicinal Chemistry Letters, 2007
A novel series of 2-aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides have been identified as potent antivirals against human herpesviruses. These compounds demonstrate broad-spectrum inhibition of the herpesvirus polymerases HCMV, HSV-1, EBV, and VZV with high specificity compared to human DNA polymerases.
Mark E, Schnute   +19 more
openaire   +2 more sources

Human Herpesvirus-4 (HHV-4)

2013
Sheina Orbell   +113 more
openaire   +1 more source

MR imaging of human herpesvirus-6-associated encephalitis in 4 patients with anterograde amnesia after allogeneic hematopoietic stem-cell transplantation.

AJNR. American journal of neuroradiology, 2006
MR imaging is typically obtained during the work-up of patients who have undergone allogeneic hematopoietic stem-cell transplant who present with unexplained change in mental status, amnesia, or seizures. Although the differential diagnosis is broad in this setting, the presence of T2 prolongation limited to the medial aspect of one or both temporal ...
R J T, Gorniak   +4 more
openaire   +1 more source

4. IgG antibodies to human herpesvirus-6 in multiple sclerosis and other neurological diseases

Journal of Neuroimmunology, 1991
E. Merelli   +5 more
openaire   +1 more source

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