Multiple sclerosis, human herpesvirus 4 and thyroid collision tumor: A case report. [PDF]
Exp Ther Med, 2020 The role of interferon β-1b (IFNβ-1b), used for multiple sclerosis (MS) therapy, in cancer occurrence is uncertain. There is evidence supporting the role of human herpesvirus 4 [Epstein-Barr virus (EBV)] in thyroid cancer and MS. Simultaneous occurrence of papillary and medullary carcinomas is rare, and its association with MS in a young woman raises ...
Sirbu AM +5 more
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Human herpesvirus 4 and adaptive immunity in Alzheimer's disease. [PDF]
Signal Transduct Target Ther, 2020 Kang JS, Liu PP.
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Inherited IRAK-4 Deficiency in Acute Human Herpesvirus-6 Encephalitis
Journal of Clinical Immunology, 2022 Human herpesvirus-6 (HHV-6) infection can rarely cause life-threatening conditions, such as encephalitis, in otherwise healthy children, with unclear pathogenesis. We studied a child who presented with acute HHV-6 encephalitis at the age of 10 months and who was homozygous for a novel missense mutation in IRAK4, encoding interleukin-1 receptor ...
Zeynep Güneş Tepe +6 more
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Evidence of Human Herpesvirus 6 Infection in 4 Immunocompetent Patients with Encephalitis [PDF]
Clinical Infectious Diseases, 2005 We describe 4 patients with encephalitis due to possible reactivation of human herpesvirus 6 (HHV-6) infection who were enrolled in the California Encephalitis Project. All were immunocompetent and had HHV-6 loads determined in cerebrospinal fluid specimens. Tests for detection of HHV-6 should be considered for individuals with encephalitis.
Erin, Isaacson +7 more
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Bovine Herpesvirus 4 Induces Apoptosis of Human Carcinoma Cell Lines In vitro and In vivo [PDF]
Cancer Research, 2005 Abstract The idea of using oncolytic viruses for the treatment of cancers was proposed a century ago. During the last two decades, viruses able to replicate specifically in cancer cells and to induce their lysis were identified and were genetically modified to improve their viro-oncolytic properties.
Gillet, Laurent +4 more
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Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Open Reading Frame 4 Protein (Kaposica) Is a Functional Homolog of Complement Control Proteins [PDF]
Journal of Virology, 2003 ABSTRACTThe genome analysis of Kaposi's sarcoma-associated herpesvirus (KSHV) has revealed the presence of an open reading frame (ORF 4) with sequence homology to complement control proteins. To assign a function to this protein, we have now expressed this ORF using thePichiaexpression system and shown that the purified protein inhibited human ...
Jayati, Mullick +4 more
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Replication of Bovine Herpesvirus Type 4 in Human Cells In Vitro [PDF]
Journal of Clinical Microbiology, 1998 ABSTRACTA reference strain (Movár 33/63) of bovine herpesvirus type 4 (BHV-4) was inoculated into 14 different human cell lines and five primary cell cultures representing various human tissues. BHV-4 replicated in two embryonic lung cell lines, MRC-5 and Wistar-38, and in a giant-cell glioblastoma cell culture.
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CXC-Chemokine Receptor 4 Is Not a Coreceptor for Human Herpesvirus 7 Entry into CD4+T Cells [PDF]
Journal of Virology, 2000 ABSTRACTHuman herpesvirus 7 (HHV-7) is a T-lymphotropic virus which utilizes the CD4 receptor as its main receptor to enter the target cells. Hence, HHV-7 can interfere with human immunodeficiency virus type 1 (HIV-1) infection in CD4+T cells. It was recently suggested that the CXC chemokine receptor 4 (CXCR4), which was found to be a crucial ...
Y, Zhang +3 more
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Acta virologica, 2020 The aim of this work was to give an overview of murid herpesvirus 4 (MuHV-4) (synonyms: murine gammaherpesvirus 68, mouse herpesvirus strain 68), the first model for the study of human and animal oncogenic gammaherpesviruses. Based on our results confirming similarity of murine gammaherpesvirus 68 (MHV-68) to another gammaherpesvirus, human oncogenic ...
J, Mistríková, K, Briestenská
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Inibidores de Ebna1 como alvos para terapias associadas a oncogênese do herpesvírus humano 4 / Ebna1 inhibitors as targets for therapies associated with oncogenesis of human herpesvirus 4 [PDF]
Brazilian Journal of Health Review, 2021 Introdução: O vírus Epstein-Barr (EBV) ou Herpesvírus Humano 4 (HHV-4) está associado ao carcinoma nasofaríngeo e diferentes malignidades em pacientes infectados, as taxas de mortalidade destacam a necessidade de pesquisas direcionadas a oncogênese causada pelo vírus.
Padilha, Marcos Daniel Mendes +7 more
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