Results 31 to 40 of about 89,995,705 (214)

The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin [PDF]

open access: yes, 2010
Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu ...
Wilson, Sam J.   +48 more
core   +1 more source

Construction and characterization of a glycoprotein E deletion mutant of bovine herpesvirus type 1.2 strain isolated in Brazil [PDF]

open access: yes, 2002
This paper describes the construction and characterization of a Brazilian strain of bovine herpesvirus type 1.2a (BoHV-1.2a) with a deletion of the glycoprotein E (gE) gene. The deletion was introduced by co-transfection of a deletion fragment containing
Rijsewijk, F.A.M.   +4 more
core   +1 more source

Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]

open access: yes, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews   +14 more
core   +1 more source

Next⁃generation sequencing technology in the diagnosis of five patients with human herpesvirus encephalitis/meningitis

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN   +10 more
doaj  

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

open access: yes, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael   +9 more
core   +1 more source

Epstein-Barr Virus DNA Enhances Diptericin Expression and Increases Hemocyte Numbers in Drosophila melanogaster via the Immune Deficiency Pathway

open access: yesFrontiers in Microbiology, 2018
Infection with the Epstein-Barr virus (EBV) is associated with several malignancies and autoimmune diseases in humans. The following EBV infection and establishment of latency, recurrences frequently occur resulting in potential viral DNA shedding, which
Nour Sherri   +5 more
doaj   +1 more source

Epstein-Barr virus-positive T/NK-cell lymphoproliferative diseases in children and adolescents [PDF]

open access: yesPrecision and Future Medicine, 2018
In primary Epstein-Barr virus (EBV) infection, the virus may infect T-cells or natural killer (NK)-cells and can cause T- and NK-cell (T/NK-cell) lymphoproliferative disease, which encompasses several disease entities with a broad clinicopathological ...
Young-Hyeh Ko
doaj   +1 more source

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

open access: yes, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael   +5 more
core   +1 more source

Heterogeneity of viral IL-6 expression in HHV-8-associated diseases. [PDF]

open access: yes, 2007
In order to characterize the expression of the viral interleukin-6 (vIL-6) homologue in various human herpesvirus 8 (HHV-8)-associated diseases, in situ hybridization and immunohistochemistry were applied to formalin-fixed specimens.
Cesarman, Ethel   +9 more
core   +1 more source

Multiple human herpesvirus-8 infection [PDF]

open access: yes, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Teo, CG   +7 more
core  

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