Results 31 to 40 of about 637,901 (279)

Epstein-Barr Virus DNA Enhances Diptericin Expression and Increases Hemocyte Numbers in Drosophila melanogaster via the Immune Deficiency Pathway

Frontiers in Microbiology, 2018
Infection with the Epstein-Barr virus (EBV) is associated with several malignancies and autoimmune diseases in humans. The following EBV infection and establishment of latency, recurrences frequently occur resulting in potential viral DNA shedding, which
Nour Sherri, Noor Salloum, Carine Mouawad, Nathaline Haidar-Ahmad, Margret Shirinian, Elias A. Rahal   +5 more
doaj   +1 more source

Epstein-Barr virus-positive T/NK-cell lymphoproliferative diseases in children and adolescents [PDF]

Precision and Future Medicine, 2018
In primary Epstein-Barr virus (EBV) infection, the virus may infect T-cells or natural killer (NK)-cells and can cause T- and NK-cell (T/NK-cell) lymphoproliferative disease, which encompasses several disease entities with a broad clinicopathological ...
Young-Hyeh Ko
doaj   +1 more source

A systematic review of the impact of psychosocial factors on immunity: Implications for enhancing BCG response against tuberculosis. [PDF]

, 2019
Background: Tuberculosis (TB) remains an urgent global public health priority, causing 1.5 million deaths worldwide in 2018. There is evidence that psychosocial factors modulate immune function; however, how this may influence TB risk or BCG vaccine ...
Boccia, D, Dowd, JB, Fletcher, H, Hayward, SE, Nellums, LB, Wurie, F   +5 more
core   +2 more sources

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara, Faggioni, Alberto, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Granato, Marisa, Romeo, Maria Anele, Santarelli, Roberta, Tiano, Mariangela Sara   +7 more
core   +2 more sources

Next⁃generation sequencing technology in the diagnosis of five patients with human herpesvirus encephalitis/meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To evaluate the value of next⁃generation sequencing (NGS) of cerebrospinal fluid (CSF) in the diagnosis of human herpesvirus encephalitis/meningitis.
Ke JIN, Xiao-juan WANG, Hong-zhi GUAN, Ling-zhi QIN, Ya-zhen JIA, Ke-ke ZHOU, Hai-chang MA, Yue WANG, Fang WANG, Li XING, Wei LI   +10 more
doaj  

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, Filardi, M, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TORRISI, Maria Rosaria   +7 more
core   +1 more source

Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes

, 2008
By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin, C. Thurner, D.S.H. Chew, F. Lillo, F. Lillo, F. Lillo, F. Ratcliff, G.P. Schroth, H.O. Smith, J.S. Mattick, M. Spanò, M. Spanò, M.Y. Leung, P. Rice, P. Simmonds, P.E. Warburton, R. Cox, R. N. Mantegna, R.C. Lee, S. Miccichè, S.R. Eddy   +20 more
core   +1 more source

Sensitive and Rapid Dual One-Tube Recombinase Aided PCR Assays for the Simultaneous Detection of Cytomegalovirus, Epstein-Barr Virus, Human Herpesvirus 6, and Herpes Simplex Virus 1/2 in Whole Blood From Children Undergoing Hematopoietic Stem Cell Transplantation. [PDF]

J Med Virol
ABSTRACT Early, rapid, and sensitive detection of cytomegalovirus (CMV), Epstein‐Barr virus (EBV), human herpesvirus 6 (HHV‐6), and herpes simplex virus Types 1/2 (HSV‐1/2) is critical for improving clinical outcomes in pediatric hematopoietic stem cell transplantation (HSCT).
Zhao L, Zhao M, Gao Y, Tie Y, Guo Y, Zhang S, Wang Y, Ma D, Shao Z, Feng Z.   +9 more
europepmc   +2 more sources

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

RNA-binding protein CPEB1 remodels host and viral RNA landscapes. [PDF]

, 2016
Host and virus interactions occurring at the post-transcriptional level are critical for infection but remain poorly understood. Here, we performed comprehensive transcriptome-wide analyses revealing that human cytomegalovirus (HCMV) infection results in
Aigner, Stefan, Ares, Manuel, Batra, Ranjan, Belzile, Jean-Philippe, Bos, Tomas J, Clark, Elizabeth, Donohue, John Paul, Gelboin-Burkhart, Chelsea, Huang, Hui, Huelga, Stephanie C, Rigo, Frank, Roberts, Brett T, Sathe, Shashank, Spector, Deborah H, Stark, Thomas J, Wheeler, Emily C, Yee, Brian A, Yeo, Gene W   +17 more
core   +2 more sources