Results 11 to 20 of about 20,017,480 (259)

Inherited IRAK-4 Deficiency in Acute Human Herpesvirus-6 Encephalitis

Journal of Clinical Immunology, 2022
Human herpesvirus-6 (HHV-6) infection can rarely cause life-threatening conditions, such as encephalitis, in otherwise healthy children, with unclear pathogenesis. We studied a child who presented with acute HHV-6 encephalitis at the age of 10 months and
Tepe, Zeynep Güneş, Belkaya, Serkan, Aytekin, Caner, Tank, Umut, Özer, Murat, Yazıcı, Yılmaz Yücehan, Köse, Ladin Işık   +6 more
core   +6 more sources

Human herpesvirus type 4 combined with Brucella abortus meningitis case report

BMC Infectious Diseases
Objective To observe and analyse the clinical characteristics, diagnosis and treatment of Human herpesvirus type 4 combined with Brucella abortus meningitis, in order to improve clinicians’ understanding of this disease.
Jingjing Yang, Feixiang Zhang, Xiaolong Guo, Jiahui Liu   +3 more
doaj   +3 more sources

Herpesvirus and Adenotonsillar Hypertrophy in Chinese Children: An Epidemiological and Clinical Analysis. [PDF]

World J Otorhinolaryngol Head Neck Surg
ABSTRACT Objective To investigate the possible association between adenotonsillar hypertrophy (ATH) and herpesviral infections in children, and to examine correlations between specific viral detection and clinical characteristics. Methods We enrolled 43 children aged 3–14 years with ATH (mean age 76.56 ± 25.65 months; 31 boys).
Ji TT, Fan M, Yu D, Ni X, Li XD, Wang XY, Lu L, Su W, Tang LX, Zhang W, Xiao X, Han Y, Mei L, Wang SC.   +13 more
europepmc   +2 more sources

Evidence of Human Herpesvirus 6 Infection in 4 Immunocompetent Patients with Encephalitis [PDF]

Clinical Infectious Diseases, 2005
We describe 4 patients with encephalitis due to possible reactivation of human herpesvirus 6 (HHV-6) infection who were enrolled in the California Encephalitis Project. All were immunocompetent and had HHV-6 loads determined in cerebrospinal fluid specimens. Tests for detection of HHV-6 should be considered for individuals with encephalitis.
Erin, Isaacson, Carol A, Glaser, Bagher, Forghani, Zahwa, Amad, Mark, Wallace, Robert W, Armstrong, Maurice M, Exner, Scott, Schmid   +7 more
openaire   +2 more sources

Comprehensive Viral Detection and Profiling of Plasma Cell-Free RNA in Patients With Suspected Hemophagocytic Lymphohistiocytosis. [PDF]

J Med Virol
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a severe, rapidly progressive disease. While viral infection is considered a common etiology of pediatric HLH, specific causative viruses other than the Epstein‐Barr virus (EBV) have been rarely identified.
Fukuda Y, Horiba K, Hashino M, Kawabe S, Miura H, Kawamura Y, Tanaka M, Suzuki T, Torii Y, Muramatsu H, Takahashi Y, Yoshikawa T, Kawada JI.   +12 more
europepmc   +2 more sources

HHV-6-Positive Meningitis in an Immunocompetent Adult: Diagnostic Challenges in Distinguishing Active Infection From Chromosomal Integration: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Consider human herpesvirus 6 (HHV‐6) in immunocompetent adults with viral meningitis when standard tests are negative. Qualitative CSF PCR requires cautious interpretation because it cannot exclude chromosomally integrated HHV‐6. Serial CSF improvement and rapid clinical recovery may support probable self‐limited infection and help avoid ...
Taha HM, Zahran A, Hajjeh O, AbuBaha B, AbuBaha M, Marouf O.   +5 more
europepmc   +2 more sources

Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]

, 2015
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA, Breuer, J, Gompels, UA, Tweedy, J, Depledge, D, Donaldson, CD   +5 more
core   +1 more source

Bovine Herpesvirus 4 Induces Apoptosis of Human Carcinoma Cell Lines In vitro and In vivo [PDF]

Cancer Research, 2005
Abstract The idea of using oncolytic viruses for the treatment of cancers was proposed a century ago. During the last two decades, viruses able to replicate specifically in cancer cells and to induce their lysis were identified and were genetically modified to improve their viro-oncolytic properties.
Gillet, Laurent, Dewals, Benjamin G, Farnir, Frédéric, de Leval, Laurence, Vanderplasschen, Alain   +4 more
openaire   +3 more sources

Herpesvirus-associated acute urticaria: an age matched case-control study. [PDF]

PLoS ONE, 2013
BACKGROUND: Acute and recurrent acute urticaria are often associated with multiple factors including infections and recent data suggest a role for herpesviruses.
Arianna Mareri, Stuart P Adler, Giovanni Nigro   +2 more
doaj   +1 more source

Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Open Reading Frame 4 Protein (Kaposica) Is a Functional Homolog of Complement Control Proteins [PDF]

Journal of Virology, 2003
ABSTRACTThe genome analysis of Kaposi's sarcoma-associated herpesvirus (KSHV) has revealed the presence of an open reading frame (ORF 4) with sequence homology to complement control proteins. To assign a function to this protein, we have now expressed this ORF using thePichiaexpression system and shown that the purified protein inhibited human ...
Jayati, Mullick, John, Bernet, Akhilesh K, Singh, John D, Lambris, Arvind, Sahu   +4 more
openaire   +2 more sources