Results 41 to 50 of about 90,152,844 (200)
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li +9 more
wiley +1 more source
Infectious mononucleosis, beyond what is seen
Introduction: infectious mononucleosis is an infection caused by various viruses, the most common being the Epstein-Barr Virus, which affects adolescents and young adults.
Danilo Mesa Rincon +2 more
doaj +1 more source
The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid ...
Luciana Cristina Fagundes Gequelin +4 more
doaj +1 more source
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen +13 more
wiley +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Objective: To identify the frequency and types of complications in children and adolescents hospitalized for infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV), as well as possible clinical and laboratory manifestations associated with ...
Isabella Sousa Araujo +1 more
doaj +1 more source
Seven‐year surveillance reveals a cold‐adapted OsHV‐1 lineage in blood clams, with disease onset at 13°C—3–5°C lower than in oysters—and identifies asymptomatic carriers and facility effluent as key transmission routes. ABSTRACT Ostreid herpesvirus 1 (OsHV‐1) poses a major threat to bivalve aquaculture, but its impact on blood clams (Anadara ...
Xiang Zhang +7 more
wiley +1 more source
Gene expression studies of lytic infection and chromosomal integration of human herpesvirus 6. [PDF]
Human herpesvirus 6 (HHV-6) was discovered in 1986 in patients with lymphoproliferative diseases and it has a predominant tropism for CD4+ T cells in vitro and in vivo.
Tsao, E.H.F.
core
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk +7 more
wiley +1 more source

