Results 41 to 50 of about 609,366 (225)

Inhibition of human herpesvirus 6 replication by 9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (2HM-HBG) and other antiviral compounds [PDF]

Antimicrobial Agents and Chemotherapy, 1990
The in vitro susceptibilities of human herpesvirus 6 to foscarnet; the guanosine analogs acyclovir, ganciclovir, and two isomers of 9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine; and the thymidine analogs 3'-azido-3'-deoxythymidine and 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil were investigated.
A, Akesson-Johansson, J, Harmenberg, B, Wahren, A, Linde   +3 more
openaire   +2 more sources

Usefulness of Herpes Consensus PCR methodology to routine diagnostic testing for herpesviruses infections in clinical specimens

Virology Journal, 2007
The purposes of the study were to assess the usefulness of simultaneously amplifying herpes simplex virus 1 and 2, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and human herpesvirus 6 DNA in various clinical specimens and to analyze ...
Priavali Efthalia, Gartzonika Constantina, Kalogeropoulos Christos, Vrioni Georgia, Levidiotou Stamatina   +4 more
doaj   +1 more source

Herpesvirus infections in ARVI episodes in children [PDF]

РМЖ. Мать и дитя, 2023
T.A. Ruzhentsova1,2, R.V. Popova3, A.A. Garbuzov1, E.K. Shushakova4, I.N. Khalyastov2,5, N.A. Meshkova6 1G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology of the Federal Service for the Oversight of Consumer Protection ...
T.A. Ruzhentsova, R.V. Popova, A.A. Garbuzov, E.K. Shushakova, I.N. Khalyastov, N.A. Meshkova   +5 more
doaj  

Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant

American Journal of Hematology, EarlyView.
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen, Roland Bassett, Rohtesh S. Mehta, Betul Oran, Fareed Khawaja, Ella J. Ariza‐Heredia, Yosra Aljawai, Amanda Olson, May Daher, Portia Smallbone, Katayoun Rezvani, Partow Kebriaei, Uday Popat, Richard Champlin, Roy F. Chemaly, Elizabeth J. Shpall   +15 more
wiley   +1 more source

Mining metagenomes and metatranscriptomes unveils viruses associated with cutaneous squamous cell carcinoma in hematopoietic stem cell transplant recipients

Microbiology Spectrum
We investigated the presence of viral DNA and RNA in cutaneous squamous cell carcinoma (cSCC) tumor and normal tissues from nine individuals with a history of hematopoietic stem cell transplantation (HCT).
Jana K. Dickter, Yuqi Zhao, Vishwas Parekh, Huiyan Ma, Badri G. Modi, Wai-Yee Li, Saro H. Armenian, Xiwei Wu, Farah R. Abdulla   +8 more
doaj   +1 more source

Tetranucleotide Profile of Herpesvirus DNA

Журнал микробиологии, эпидемиологии и иммунобиологии, 2020
Introduction. Herpesvirus DNAs (about 90% of the total genomic sequences of the Herpesvirales family presented in GenBank) contain at a minimum concentration one of the two tetranucleotides, CTAG or TCGA.
Felix P. Filatov, Alexander V. Shargunov
doaj   +1 more source

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Proteomic characterization of murid herpesvirus 4 extracellular virions. [PDF]

PLoS ONE, 2013
Gammaherpesvirinae, such as the human Epstein-Barr virus (EBV) and the Kaposi's sarcoma associated herpesvirus (KSHV) are highly prevalent pathogens that have been associated with several neoplastic diseases.
Sarah Vidick, Baptiste Leroy, Leonor Palmeira, Bénédicte Machiels, Jan Mast, Sylvie François, Ruddy Wattiez, Alain Vanderplasschen, Laurent Gillet   +8 more
doaj   +1 more source

Effect of (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) and AZT–lipid–PFA on human herpesvirus-6B infected cells [PDF]

Journal of Clinical Virology, 2009
Human herpesvirus-6 (HHV-6) has been associated with a wide spectrum of diseases. (r)-9-[4-Hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) is an acyclic guanosine analogue that is structurally similar to acyclovir and is in clinical development for treatment of herpesvirus infections. H2G has been found to have activity against HSV type 1, HSV type 2, and
Karen, Yao, Christel, Hoest, Farzin, Rashti, Timm C, Schott, Steven, Jacobson   +4 more
openaire   +2 more sources