Results 51 to 60 of about 20,017,480 (259)

Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant

Revista Brasileira de Hematologia e Hemoterapia, 2011
The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid ...
Luciana Cristina Fagundes Gequelin, Irina N Riediger, Sueli M Nakatani, Alexander W Biondo, Carmem M Bonfim   +4 more
doaj   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

A Very Strong Enhancer Is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus [PDF]

, 1985
A strong transcription enhancer was identified in the genomic DNA (235 kb) of human cytomegalovirus (HCMV), a ubiquitous and severe pathogen of the herpesvirus group.
Boshart, Michael, Schaffner, Walter, Weber, Frank, Jahn, Gerhard, Dorsch-Häsler, Karoline, Fleckenstein, Bernhard   +5 more
core   +1 more source

Infectious mononucleosis, beyond what is seen

Revista Ciencias Biomédicas
Introduction: infectious mononucleosis is an infection caused by various viruses, the most common being the Epstein-Barr Virus, which affects adolescents and young adults.
Danilo Mesa Rincon, Silvia Suárez Mantilla, Claudia Durán Chacón   +2 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Gene expression studies of lytic infection and chromosomal integration of human herpesvirus 6. [PDF]

, 2008
Human herpesvirus 6 (HHV-6) was discovered in 1986 in patients with lymphoproliferative diseases and it has a predominant tropism for CD4+ T cells in vitro and in vivo.
Tsao, E.H.F.
core  

Heterogeneity of viral IL-6 expression in HHV-8-associated diseases. [PDF]

, 2007
In order to characterize the expression of the viral interleukin-6 (vIL-6) homologue in various human herpesvirus 8 (HHV-8)-associated diseases, in situ hybridization and immunohistochemistry were applied to formalin-fixed specimens.
Cesarman, Ethel, Nicholas, John, Cannon, Jennifer S., Murray, Paul G., Ambinder, Richard F., Orenstein, Jan M., Mann, Risa B., DiGiuseppe, Joseph A., Hayward, Gary S., Browning, Philip J.   +9 more
core   +1 more source

COMPLICATIONS OF INFECTIOUS MONONUCLEOSIS DUE TO EPSTEIN-BARR VIRUS IN CHILDREN AND ADOLESCENTS HOSPITALIZED IN A TERTIARY PEDIATRIC HOSPITAL IN SOUTHERN BRAZIL: A 10-YEAR ANALYSIS (2014‒2024)

Brazilian Journal of Infectious Diseases
Objective: To identify the frequency and types of complications in children and adolescents hospitalized for infectious mononucleosis (IM) caused by Epstein-Barr virus (EBV), as well as possible clinical and laboratory manifestations associated with ...
Isabella Sousa Araujo, Emanuela da Rocha Carvalho   +1 more
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]

, 2008
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Wiertz, E.J.H.J., Rezende, Marisa Marcondes, Thomas C Mettenleiter, Jacques J Neefjes, Wang, Ying, Koch, J., Mirjam H M Heemskerk, Loch Sandra, Marieke C Verweij, Daus, Franz, Nikolaus Osterrieder, Neefjes, J.J., Tampe, R., Chowdhury, Shafiqul I., Osterrieder, Nikolaus, Loch, S., Edwin Quinten, Rijsewijk, Frans A. M., Quinten, E., Neefjes, Jacques J., Ressing, Maaike E., Lipinska, A.D., Krystyna Bieńkowska-Szewczyk, Verweij Marieke C., Koch Joachim, Danijela Koppers-Lalic, Neefjes Jacques J., Wiertz, Emmanuel J. H. J., Koppers-Lalic, Danijela, Mettenleiter, T.C., Lipińska Andrea D., Rezende Marisa Marcondes, Ressing Maaike E., Emmanuel J H J Wiertz, Lipinska, Andrea D., Tampé Robert, Verweij, M.C., Ressing, M.E., Ying Wang, Wang, Y., Koch, Joachim, Heemskerk, Mirjam H. M., Sandra Loch, Marisa Marcondes Rezende, Tampé, Robert, Daus, F.J., Reits, E.A., Wiertz Emmanuel J. H. J., Shafiqul I Chowdhury, Loch, Sandra, Koppers-Lalic Danijela, Osterrieder, N., Quinten, Edwin, Rezende, M.M., Robert Tampé, Verweij, Marieke C., Joachim Koch, Franz Daus, Mettenleiter Thomas C., Bienkowska-Szewczyk, K., Rijsewijk, F.A.M., Eric A Reits, Heemskerk Mirjam H. M., Mettenleiter, Thomas C., Maaike E Ressing, Reits Eric A., Marcondes Rezende, Marisa, Chowdhury, S.I., Osterrieder Nikolaus, Daus Franz, Quinten Edwin, Koppers-Lalic, D., Reits, Eric A., Bienkowska-Szewczyk, Krystyna, Andrea D Lipińska, Frans A M Rijsewijk, Bieńkowska-Szewczyk Krystyna, Wang Ying, Rijsewijk Frans A. M., Heemskerk, M.H.M., Chowdhury Shafiqul I.   +80 more
core   +2 more sources