Results 51 to 60 of about 609,366 (225)

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

CNS INFECTIONS CAUSED BY VIRUSES OF THE HERPESVIRIDAE FAMILY: CASE ANALYSIS IN A TERTIARY INFECTIOUS DISEASES CENTER

Brazilian Journal of Infectious Diseases
Introduction/Objectives: The Herpesviridae family includes viruses with latency capacity, such as HSV-1, HSV-2, VZV, CMV, and Human herpesvirus 6, which can cause neurological manifestations such as meningitis, encephalitis, and encephalomyelitis.
Luís Arthur Brasil Gadelha Farias, Lorena Alves Brito, Bruno Cavalcante Fales de Brito Alves, José Leonardo da Silveira Morais, Osvaldo Mariano Viana Neto, Ednaldo Pereira Lima Sobrinho, Tânia Mara Silva Coelho, Maura Salaroli de Oliveira, Lauro Vieira Perdigão Neto, Antonio Silva Lima Neto   +9 more
doaj   +1 more source

Features of Human Herpesvirus-6A and -6B Entry

Advances in Virology, 2012
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj   +1 more source

Sequencing of bovine herpesvirus 4 v.test strain reveals important genome features

Virology Journal, 2011
Background Bovine herpesvirus 4 (BoHV-4) is a useful model for the human pathogenic gammaherpesviruses Epstein-Barr virus and Kaposi's Sarcoma-associated Herpesvirus.
Gillet Laurent, Vanderplasschen Alain, Lété Céline, Machiels Bénédicte, Palmeira Leonor   +4 more
doaj   +1 more source

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

Epileptic Disorders, EarlyView.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu, Hüseyin Öztoprak, Özlem Yayıcı Köken, Hatice Demir, Mehpare Sarı Yanartaş, Deniz Yılmaz, Burçin Şanlıdağ, Ayşegül Neşe Çıtak Kurt   +7 more
wiley   +1 more source

Active herpesviruses are associated with intensive care unit (ICU) admission in patients pulmonary infection and alter the respiratory microbiome

Frontiers in Microbiology
BackgroundThe Herpesviridae family contains several human-related viruses, which are able to establish colonizing and latency in the human body, posing a significant threat to the prognosis of patients.
Zhiguang Liu, Chun-jian Qi, Yujia Shi, Tianyu Li, Yuan Fang, Qian Zhang, Qian Zhang   +6 more
doaj   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

Considerations about gastric cancer proteomics

Revista do Colégio Brasileiro de Cirurgiões
The frequency of molecular studies aimed to analyze promoter methylation of tumor suppressor genes and global proteomics in gastric carcinogenesis is increasing.
CARLOS EDUARDO CARVALHO, THAÍS MESSIAS MCCORMICK, PAULO COSTA CARVALHO, JULIANA DE SALDANHA DA GAMA FISCHER, PRISCILA FERREIRA DE AQUINO, GUILHERME PINTO BRAVO NETO, MARIA DA GLÓRIA DA COSTA CARVALHO   +6 more
doaj   +1 more source

A Case of Severe Chronic Active Epstein-Barr Virus Infection with Aplastic Anemia and Hepatitis

The Korean Journal of Gastroenterology, 2016
Epstein-Barr virus (EBV) causes various acute and chronic diseases. Chronic active EBV infection (CAEBV) is characterized by infectious mononucleosis-like symptoms that persist for more than 6 months with high viral loads in peripheral blood and/or an ...
Ja In Lee, Sung Won Lee, Nam Ik Han, Sang Mi Ro, Yong-Sun Noh, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon   +8 more
doaj   +1 more source