ABSTRACT Chronic kidney disease (CKD) is associated with inflammation and cardiovascular complications and is partly exacerbated by the uremic toxin indoxyl sulfate (IS). IS is known to activate the aryl hydrocarbon receptor (AhR) to promote vascular inflammation.
Hiroyuki Sasaki +8 more
wiley +1 more source
Human herpesvirus 6 (HHV-6) infection and risk of Alzheimer's disease: a systematic review and meta-analysis. [PDF]
Bastan F +4 more
europepmc +1 more source
ABSTRACT Background Herpes zoster (HZ), resulting from reactivation of latent varicella‐zoster virus (VZV), imposes a significant burden on immunocompromised patients, particularly those with hematological malignancies and recipients of hematopoietic stem cell transplants (HSCT).
Enrica Antonia Martino +10 more
wiley +1 more source
Global Prevalence and Cancer Risk of Epstein-Barr Virus and Human Papillomavirus Coinfection in Breast Cancer: A Systematic Review and Meta-Analysis. [PDF]
Karen AA +6 more
europepmc +1 more source
Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy
The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores how human tumour viruses manipulate the ubiquitination system to complete their life cycle, evade immunity and promote cancer.
Oscar Trejo‐Cerro +2 more
wiley +1 more source
Discovering the complete enhancer map of human herpesviruses using a natural language processing model. [PDF]
Roy Chowdhury N +3 more
europepmc +1 more source
AIRE's Complex Role Beyond Promiscuous Gene Expression
ABSTRACT Central tolerance, established in the thymus, ensures T cells are nonreactive to self‐antigens while maintaining a functional immune repertoire. Medullary thymic epithelial cells (mTECs) and thymic dendritic cells (DCs) play a crucial role in this mechanism by orchestrating the selection and deletion of autoreactive thymocytes, a process ...
Pärt Peterson
wiley +1 more source
Bidirectional causal relationships between antibody-mediated immune responses and autoimmune diseases: Insights from Mendelian randomization analysis. [PDF]
Huang L, Han L, Lin Q.
europepmc +1 more source
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. The last decade has seen accumulating evidence for microRNA dysregulation in circulating extracellular vesicles (EVs); however, assessing reproducibility between studies remains challenging ...
Aliyah Zaman +2 more
wiley +1 more source
Atypical manifestation of human herpes virus-6 encephalitis with extra-limbic lesions: a case report. [PDF]
Ahn SH, Ahn SJ, Chu K.
europepmc +1 more source

