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Biology of bovine herpesvirus 5

Veterinary Journal, 2010
Bovine herpesvirus 5 (BoHV-5) is an alphaherpesvirus responsible for meningoencephalitis in young cattle and is closely antigenically and genetically related to bovine herpesvirus 1 (BoHV-1). Both viruses have common aspects in their pathogenesis: (1) they infect epithelial cells at the portal of entry and (2) they establish a latent infection in the ...
Benoit Muylkens, Etienne Thiry, Maria Paula del Médico Zajac   +2 more
exaly   +5 more sources

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Primary Infection, Latency, and Reactivation of Bovine Herpesvirus Type 5 in the Bovine Nervous System

Veterinary Pathology, 2002
Bovine herpesvirus type 5 (BHV-5) infection in calves causes meningoencephalitis, a fatal disease highly prevalent in South America. To study the pathogenesis of BHV-5 infection in cattle, 12 calves (group 1: acute infection) and 11 calves (group 2: latent infection) were intranasally inoculated with an Argentinean BHV-5 isolate at 108 and 104.7 ...
S E Perez, M R Leunda, A C Odeon
exaly   +3 more sources

A comparative analysis of envelope and tegument proteins of suid herpesvirus 1, bovine herpesvirus 1 and bovine herpesvirus 5

Archives of Virology, 2010
The aim of this study was to analyze the disordered regions (DRs) in the envelope and tegument proteins of three closely related herpesviruses: bovine herpesvirus 1, bovine herpesvirus 5 and suid herpesvirus 1. Tegument proteins showed a greater percentage of DRs than the envelope proteins did.
A A, Fonseca, M B, Heinemann, R C, Leite, J K P, Reis   +3 more
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Recrudescence of bovine herpesvirus-5 in experimentally infected calves

American Journal of Veterinary Research, 1982
SUMMARY A latent infection of bovine herpesvirus-5 (bhv-5) was established in 4 calves. These calves, plus 2 controls, were given dexamethasone (dm) to reactivate the latent virus. The 4 principal calves developed antibodies to bhv-5 by postinoculation day (pid) 21. Antibody titers increased until pid 42 before decreasing to low levels at pid 75. After
L A, Krogman, J P, McAdaragh
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First report of bovine herpesvirus 5 in bull semen

Archives of Virology, 2012
BoHV-5 was detected in one of several extended semen samples from a healthy donor bull during routine virus screening. This was achieved by polymerase chain reaction assay (PCR) and virus isolation, with primary identification by the fluorescent antibody test.
Majela, Rodríguez, Maritza, Barrera, Oliberto, Sánchez, Eya Caridad, Rodríguez, Nadia, Martínez, Natalie C, Parra, Jorge R, Toledo   +6 more
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Effects of bovine Herpesvirus Type 5 on development of in vitro–produced bovine embryos

Theriogenology, 2010
Bovine (Bos indicus) herpesviruses have been associated with reproductive disease. Type 1, the most studied species, is best known for its reproductive and respiratory effects. Type 5 (BoHV-5) has been detected in bull semen and aborted fetuses but not in oocytes and embryos.
Silva-Frade, C., Martins, A., Borsanelli, A. C., Cardoso, T. C.   +3 more
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A simple method of infecting rabbits with Bovine herpesvirus 1 and 5

Journal of Virological Methods, 2008
This report describes an alternative technique to inoculate rabbits and to reproduce infection by Bovine herpesvirus 1 and 5. First, the nostrils are anaesthetized by aspersion with local anaesthetic. A few seconds later, and after proving the insensitivity of the zone, the rabbits are put on their back legs with their nostrils upwards and the inoculum
A R, Valera, C L, Pidone, A R, Massone, M A, Quiroga, J G, Riganti, S G, Corva, C M, Galosi   +6 more
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Vaccination with a gE-negative bovine herpesvirus type 1 vaccine confers insufficient protection to a bovine herpesvirus type 5 challenge

Vaccine, 2006
In the present study, cross-protection to bovine herpesvirus type 5 (BHV-5) induced by bovine herpesvirus type 1 (BHV-1) vaccination was examined following inoculation of rabbits and calves with a glycoprotein E (gE)-negative BHV-1 vaccine and subsequent challenge with BHV-5. Rabbits (n=5) and calves (n=8) were vaccinated [five rabbits intranasally (IN)
Fernando Spilki, Ana Franco, Paulo Michel Roehe   +2 more
exaly   +4 more sources

Synthetic aminomethylnaphthoquinones inhibit the in vitro replication of bovine herpesvirus 5

Archives of Virology, 2014
Bovine herpesvirus type 5 (BoHV-5) is an etiologic agent of meningoencephalitis in cattle. The aim of this study was to evaluate the antiviral potential of a series of synthetic Mannich bases derived from lawsone and to investigate at which stage of the BoHV-5 replicative cycle the compounds might be acting.
Ana Maria V, Pinto, José Paulo G, Leite, Amanda P, Neves, Gustavo B, da Silva, Maria D, Vargas, Izabel Christina N P, Paixão   +5 more
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Efficacy of an inactivated, recombinant bovine herpesvirus type 5 (BoHV-5) vaccine

Veterinary Microbiology, 2011
Bovine herpesvirus type 5 (BoHV-5) is the causative agent of bovine herpetic encephalitis. In countries where BoHV-5 is prevalent, attempts to vaccinate cattle to prevent clinical signs from BoHV-5-induced disease have relied essentially on vaccination with BoHV-1 vaccines.
F S, Campos, D, Dezen, D A, Antunes, H F, Santos, T S, Arantes, A, Cenci, F, Gomes, F E S, Lima, W M E D, Brito, H C K, Filho, H B C R, Batista, F R, Spilki, A C, Franco, F A M, Rijsewijk, P M, Roehe   +14 more
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