Novel Entry Pathway of Bovine Herpesvirus 1 and 5 [PDF]
ABSTRACT Herpesviruses enter cells by a yet poorly understood mechanism. We visualized the crucial steps of the entry pathway of bovine herpesvirus 1 (BHV-1) and BHV-5 by transmission and scanning electron microscopy, employing cryotechniques that include time monitoring, ultrarapid freezing, and freeze substitution of cultured cells ...
Wild P +4 more
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Pathogenesis of meningoencephalitis in rabbits by bovine herpesvirus type-5 (BHV-5) [PDF]
This article describes the main aspects of bovine herpesvirus type-5 (BHV-5) neurologic infection and disease in rabbits, a candidate animal model for studying BHV-5 neuropathogenesis. Intranasal inoculation of weanling rabbits with a Brazilian BHV-5 isolate produced neurological disease and death in 78.8% (26/33) of the animals.
Silva, Adriana M. da +6 more
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Construction and characterization of a glycoprotein E deletion mutant of bovine herpesvirus type 1.2 strain isolated in Brazil [PDF]
This paper describes the construction and characterization of a Brazilian strain of bovine herpesvirus type 1.2a (BoHV-1.2a) with a deletion of the glycoprotein E (gE) gene. The deletion was introduced by co-transfection of a deletion fragment containing
Rijsewijk, F.A.M. +4 more
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Bovine Herpesvirus 5 (BHV-5) Us9 Is Essential for BHV-5 Neuropathogenesis [PDF]
ABSTRACTBovine herpesvirus 5 (BHV-5) is a neurovirulent alphaherpesvirus that causes fatal encephalitis in calves. In a rabbit model, the virus invades the central nervous system (CNS) anterogradely from the olfactory mucosa following intranasal infection.
S I, Chowdhury +5 more
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A four year longitudinal sero-epidemiological study of bovine herpesvirus type-1 (BHV-1) in adult cattle in 107 unvaccinated herds in south west England [PDF]
Background: Bovine herpesvirus type-1 (BHV-1) is an important pathogen of cattle that presents with a variety of clinical signs, including the upper respiratory tract infection infectious bovine rhinotracheitis (IBR). A seroepidemiological study of BHV-
Ramírez Villaescusa, Ana +21 more
core +1 more source
The core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin encoded by bovine herpesvirus 4 was acquired from an ancestor of the African buffalo [PDF]
peer reviewedThe Bo17 gene of bovine herpesvirus 4 (BoHV-4) is the only viral gene known to date that encodes a homologue of the cellular core 2 beta-1,6-N-acetylglucosaminyltransferase-mucin type (C2GnT-M). To investigate the origin and evolution of the
Markine-Goriaynoff, N +17 more
core +1 more source
A study was performed in 2 phases to determine the ability of 2 different modified live (MLV) bovine herpesvirus-1 (BoHV-1)vaccines to protect against conjunctivitis caused by a recent field isolate of BoHV-1.
Walz, Paul H. +3 more
core +1 more source
Endemic cattle diseases : comparative epidemiology and governance [PDF]
Cattle are infected by a community of endemic pathogens with different epidemiological properties which invoke different managerial and governmental responses. We present characteristics of pathogens that influence their ability to persist in the UK, and
McEldowney, John F. +23 more
core +1 more source
Bovine herpesvirus 5 encodes a unique pattern of microRNAs compared with bovine herpesvirus 1
Bovine herpesvirus type 5 (BoHV-5) and bovine herpesvirus 1 (BoHV-1) are two closely related viruses. However, BoHV-5 is responsible for fatal meningitis in calves, while BoHV-1 is associated with infectious rhinotracheitis in cattle, and the mechanism by which the two viruses cause different symptoms is not well understood.
Qi, Tang +5 more
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Selection and characterization of brivudin resistant bovine herpesvirus type 5 [PDF]
Bovine herpesvirus type 5 (BoHV-5) is the agent of meningoencephalitis, an important disease of cattle in South America. The neuropathogenesis of BoHV-5 infection is poorly understood and most previous research focused on the role of envelope glicoproteins in neurovirulence.
Brum, Mário Celso Sperotto +3 more
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