Results 41 to 50 of about 79,121,524 (214)

Imunogenicidade de isolados de herpesvírus bovino 5 como candidatos à vacina Immunogenicity of bovine herpesvirus 5 isolates as vaccine candidates

Ciência Rural, 2009
O herpesvírus bovino 5 (BoHV-5) é o agente da menigoencefalite herpética bovina. A doença neurológica, associada à infecção pelo BoHV-5, apresenta altas taxas de letalidade em bovinos jovens e está disseminada no Brasil.
Luiz Felipe Lourenço de Souza, Abelardo Silva Júnior, Carla Maria Batista de Freitas, Ethel Cardoso de Freitas, Eduardo Furtado Flores, Márcia Rogéria de Almeida, Mauro Pires Moraes   +6 more
doaj   +1 more source

Antiviral Property of the Fungal Metabolite 3-O-Methylfunicone in Bovine Herpesvirus 1 Infection

Microorganisms, 2022
Bovine herpesvirus type-1 (BoHV-1) is a widespread pathogen that provokes infectious rhinotracheitis and polymicrobial infections in cattle, resulting in serious economic losses to the farm animal industry and trade restrictions.
Filomena Fiorito, Claudia Cerracchio, Maria Michela Salvatore, Francesco Serra, Alessia Pucciarelli, Maria Grazia Amoroso, Rosario Nicoletti, Anna Andolfi   +7 more
doaj   +1 more source

Characterization of BoHV-5 field strains circulation and report of transient specific subtype of bovine herpesvirus 5 in Argentina

BMC Veterinary Research, 2011
Background Bovine herpesvirus 5 (BoHV-5) is a member of the subfamily Alphaherpesvirinae responsible for meningo-encephalitis in young cattle. The first case of bovine meningo-encephalitis associated with a herpesvirus infection was reported in Australia.
Thiry Julien, Palacios María, Fondevila Norberto, Combessies Gustavo, Viera Javier, Odeón Anselmo, Del Médico Zajac María P, Lomónaco Patricia M, Pérez Sandra E, Ladelfa María F, Maidana Silvina S, Muylkens Benoît, Thiry Etienne, Romera Sonia A   +13 more
doaj   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Neuropatogênese experimental da infecção pelo herpesvírus bovino tipo 5 em coelhos Experimental neuropathogenesis of bovine herpesvirus 5 infection in rabbits

Pesquisa Veterinária Brasileira, 2009
Vários aspectos da biologia do herpesvírus bovino tipo 5 (BoHV-5) têm sido estudados em coelhos, que desenvolvem infecção aguda e doença neurológica após inoculação experimental.
Eduardo Furtado Flores, Rudi Weiblen, Fernanda Silveira Flores Vogel, Renata Dezengrini, Sabrina Ribeiro de Almeida, Fernando Rosado Spilki, Paulo Michel Roehe   +6 more
doaj   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Are all bovine herpesvirus-1 reproductive disease events vaccine-induced?

, 2016
Modified-live virus (MLV) bovine herpesvirus 1 (BHV-1) vaccines have been a major part of the program to the prevention of reproductive disease in cattle. However, their use (or misuse) continues to result in major abortion storms.
Clement, T., Chase, C. C. L., Gillette, B.   +2 more
core   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source

Meningoencefalite por Herpesvirus bovino 5 em Minas Gerais: relato de caso clínico Meningoencephalitis by Bovine herpesvirus 5 in Minas Gerais state: clinical case report

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009
Relata-se um caso de meningoencefalite causada por Herpesvirus bovino 5 (BoHV-5) heritabilityem uma vaca com cinco anos de idade. O animal manifestou quadro clínico inicial de síndrome medular baixa, caracterizada por incoordenação dos membros pélvicos ...
H.M. Aquino Neto, A.U. Carvalho, E.J. Facury Filho, P.M. Ferreira, E.F. Barbosa-Stancioli, Z.I.P. Lobato, M.R. Alvarenga, A.L. Serrano, R.A. Martins, D.A.F. Afonso   +9 more
doaj   +1 more source

Investigations of presence of antibodies against bovine herpesvirus-1 in blood serum of calves prior to colostrum diet [PDF]

Veterinarski Glasnik, 2010
The paper presents the results of investigations of the presence of the bovine herpesvirus-1 (BHV-1) in samples of blood serum from 106 cows and 107 of their calves (one cow had twins).
Lazić Sava, Rogan Dragan, Petrović Tamaš, Bugarski Dejan, Lupulović Diana, Lazarević Miodrag   +5 more
doaj   +1 more source