Results 41 to 50 of about 174,898 (177)

Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]

, 2009
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr, Ulrich Koszinowski, Mühlbach, Hermine, Koszinowski, Ulrich H., Zsolt Ruzsics, Christian Mohr, Mohr, Christian A., Ruzsics, Zsolt, Hermine Mühlbach, Ulrich H. Koszinowski   +9 more
core   +1 more source

Inducing Antigen‐Specific and Functional Immune Responses in Mice Toward Bovine Herpesvirus 1 and Bovine Respiratory Syncytial Virus by Chimeric Peptides Delivered by Bovine Herpesvirus 4‐Based Vector

Immunology, EarlyView.
Bovine Alphaherpesvirus 1 (BoHV‐1) and Bovine respiratory syncytial virus (BRSV) are major drivers of respiratory disease in cattle. (A) To target both pathogens, two chimeric antigens—membrane‐linked and secreted—combining BoHV‐1 glycoprotein D and BRSV fusion glycoprotein were designed and expressed using recombinant BoHV‐4‐based vectors.
Antonino Di Lorenzo, Sergio Minesso, Chiara Cossu, Valentina Franceschi, Elisabetta Bolli, Vittorio Madia, Laura Conti, Gaetano Donofrio   +7 more
wiley   +1 more source

Vaccination Reduces Shedding of Salmonid Alphavirus Subtype 3, but Bacterial Co‐Infection Influences the Effect

Journal of Fish Diseases, EarlyView.
ABSTRACT Waterborne horizontal transmission of viral diseases in fish relies on the release of infectious virus particles (termed shedding) into the aquatic environment. Both the rate and duration of shedding are critical for efficient viral spread, making interventions that reduce shedding valuable for disease control.
Søren Grove, H. Craig Morton, Dhamotharan Kannimuthu, HyeongJin Roh, Ravikumar M. Chovatia, Ma Michelle Peñaranda, Dawit Ghebretnsae, Kai Ove Skaftnesmo   +7 more
wiley   +1 more source

Rapid, sensitive, and visible RPA-LFD assay for BoHV-1 and BoHV-5

Microbiology Spectrum
Bovine herpesvirus (BoHV) infection poses a significant threat to the healthy development of the cattle industry. BoHV-1 primarily causes infectious bovine rhinotracheitis, while BoHV-5 is associated with bovine necrotic meningoencephalitis.
Yue Wu, Wenci Zhang, Chenyang Yi, Kuijing He, Changmin Hu, Guishan Ye, Anding Zhang   +6 more
doaj   +1 more source

Dexamethasone-induced reactivation of bovine herpesvirus type 5 latent infection in experimentally infected rabbits results in a broader distribution of latent viral DNA in the brain

Brazilian Journal of Medical and Biological Research, 2006
Bovine herpesvirus type 5 (BHV-5) is a major agent of meningoencephalitis in cattle and establishes latent infections mainly in sensory nerve ganglia. The distribution of latent BHV-5 DNA in the brain of rabbits prior to and after virus reactivation was ...
S.V. Mayer, V.L. de Quadros, F.S.F. Vogel, E.R. Winkelmann, S. Arenhart, R. Weiblen, E.F. Flores   +6 more
doaj   +1 more source

Immune dysregulation in mania: A proof‐of‐concept platelet proteomics study

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Bipolar disorder (BD) is a major psychiatric condition with a multifaceted and largely unknown pathophysiology. Mania, the defining feature of BD, remains underinvestigated. Proteomics offers a powerful, data‐driven, unbiased approach to uncover biological alterations.
Paola Magioncalda, Matteo Martino, Nhi Thao Ngoc Le, Wen‐Yin Chen, Ming‐Chyi Huang, David Blum, Thierry Burnouf   +6 more
wiley   +1 more source

Ruminant alphaherpesviruses related to bovine herpesvirus 1.

, 2006
peer reviewedHerpesviruses have mainly co-evolved with their hosts for millions of years. Consequently, different related host species may have been infected by various genetically related herpesviruses.
Thiry, Etienne, Sacha Gogev, Meurens, Francois, Keuser, Veronique, François Meurens, Alain Vanderplasschen, Thiry, Julien, Julien Thiry, Véronique Keuser, Etienne Thiry, Benoît Muylkens, Gogev, Sacha, Muylkens, Benoît, Vanderplasschen, Alain   +13 more
core   +1 more source

Histophilus somni-induced thrombotic meningoencephalitis in cattle from northern Paraná, Brazil

Pesquisa Veterinária Brasileira, 2015
Thrombotic meningoencephalitis (TME) is a fatal neurological disease of cattle, predominantly from North America, that is caused by Histophilus somni with sporadic descriptions from other countries. This manuscript describes the occurrence of spontaneous
Selwyn A. Headley, Ana Paula F.R.L. Bracarense, Victor H.S. Oliveira, Gustavo R. Queiroz, Werner Okano, Alice F. Alfieri, Karina K.M.C. Flaiban, Júlio A.N. Lisbôa, Amauri A. Alfieri   +8 more
doaj   +1 more source

Integrative Phosphoproteomic Profiling Reveals Stage‐Specific Signalling and Metabolism in Equine Melanocytic Neoplasm

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Equine melanocytic neoplasms (EMN) are aggressive tumours characterised by high metastatic potential and limited therapeutic options available. However, the molecular mechanisms underlying their progression remain poorly understood. This study therefore presents the integrative phosphoproteomic analysis of EMN tissue, with the aim of ...
Paitoon Srimontri, Amornthep Kingkaw, Nawarus Prapaiwan, Rangsima Sujittosakul, Nichapat Iamkaewprasert, Jiraschaya Piputwat, Puetta Isama‐al, Thanutchanok Munkongdee, Thanapon Chotikaprakal, Petchpailin Yanyongsirikarn, Narumon Phaonakrop, Sittiruk Roytrakul, Wanwipa Vongsangnak, Parichart Tesena   +13 more
wiley   +1 more source

Enfermidades do sistema nervoso dos ruminantes no sul do Rio Grande do Sul Neurological diseases in ruminants in southern Brazil

Ciência Rural, 1998
Descrevem-se os aspectos epidemiológicos, clínicos e patológicos das enfermidades do sistema nervoso central dos ruminantes, diagnosticadas na região Sul do Rio Grande do Sul, incluindo: abiotrofia cerebelar; hipoplasia cerebelar; hipermetria hereditária;
Franklin Riet-Correa, Ana Lucia Schild, Cristina Gevehr Fernandes   +2 more
doaj   +1 more source