Results 161 to 170 of about 569,912 (280)

Endoplasmic Reticulum Stress in Cancer

MedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou, Wenlong Wang, Baizhao Li, Zhu Li, Juan Huang, Xinying Li   +5 more
wiley   +1 more source

Formalin‐fixed paraffin‐embedded (FFPE) samples help to investigate transcriptomic responses in wildlife disease

Molecular Ecology Resources, Volume 25, Issue 5, July 2025.
Abstract Infectious diseases impact numerous organisms. Knowledge of host‐pathogen interactions and host responses to infection is crucial for conservation and management. Obtaining this knowledge quickly is made increasingly possible by a variety of genomic approaches, yet, for many species the bottleneck to understanding this, remains access to ...
Allison K. Miller, Cara L. Brosnahan, Anjali Pande, Cindy F. Baker, Jemma L. Geoghegan, Jane Kitson, Neil J. Gemmell, Edwina J. Dowle   +7 more
wiley   +1 more source

SQSTM1/p62 Orchestrates Skin Aging via USP7 Degradation

Aging Cell, Volume 24, Issue 7, July 2025.
p62 exhibits diminished expression in aging skin and senescent cells. p62 serves to inhibit the accumulation of USP7 during senescence induction. The Tyr‐67 residue within the PB1 domain or Gln‐418 within the UBA domain of p62 forms a hydrogen bond with Ala‐993 of the Ubl5 domain of USP7.
Liu Chen, Xiaoping Wang, Yuchen Wang, Qingxin Yao, Yunyao Liu, Yongcheng Zhu, He Huang, Hedan Yang, Yin Yang, Yuan He, Lei Qiang   +10 more
wiley   +1 more source

A Pulmonary Abscess Caused by Porphyromonas gingivalis Infection: A Case Report and Literature Review

The Clinical Respiratory Journal, Volume 19, Issue 7, July 2025.
ABSTRACT Lung abscess is a common disease in respiratory medicine, which is a suppurative lesion caused by various pathogens, and microbiological examination is crucial for the treatment of lung abscess. Due to the widespread use of antibiotics, it is difficult to obtain reliable microbiological evidence through routine tests.
Xu Chen, Ling Wu, Ruoxi Wu, Jiajia Dong
wiley   +1 more source

Herpesvirus Infections of the Central Nervous System [PDF]

, 2019
There are over 200 herpesvirus species, of which 10 affect humans. Each of these 10 herpesviruses has a unique clinical syndrome, but common to all is their ability to cause infection and pathology in the central nervous system.
Bharucha, T, Breuer, J, Houlihan, CF
core  

Clinical characteristics and treatment of varicella zoster virus central nervous system infection in an Australian tertiary hospital

Internal Medicine Journal, Volume 55, Issue 7, Page 1152-1160, July 2025.
Abstract Background and Aim Varicella zoster virus (VZV) is a neurotropic herpesvirus. With improved access to molecular diagnostics, there is increasing recognition of VZV with central nervous system involvement. This study aimed to describe the demographic, clinical and treatment characteristics of patients admitted to an Australian tertiary hospital
Connie Lam, Eve Chen, Arthur Thevathasan, Terry Yan, Michael Moso, Joe Sasadeusz, Stephen Muhi   +6 more
wiley   +1 more source

Thoracic Ultrasonography Findings and Their Association With Respiratory Pathogens in 221 Young Beef Cattle at Fattening Farms: A Cross‐Sectional Study

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Thoracic ultrasonography (TUS) could improve antibiotic treatment selection in cattle with respiratory diseases. Hypothesis/Objectives Evaluate the association between respiratory pathogens and consolidations on TUS in feedlot cattle, at both individual and group levels. Animals A total of 221 bulls, aged 8.8 months and weighing 322.
Maud Rouault, Gilles Foucras, François Meurens, Sébastien Assié   +3 more
wiley   +1 more source

Pityriasis rosea during COVID-19 and its pathogenesis

JAAD International, 2022
Francesco Drago, MD, Giulia Ciccarese, MD, PhD   +1 more
doaj  

Immunosenescence and Inflammaging in Dogs and Cats: A Narrative Review

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT A consistent and important feature of biological aging is the change in the types and functions of cells comprising the immune system. Across various mammalian species, this change follows consistent patterns, including diminished protective capacity, leading to increased vulnerability to infectious disease, and increased low‐grade chronic ...
Brennen A. McKenzie
wiley   +1 more source

Clinical diagnosis and management of drug reaction with eosinophilia and systemic symptoms (DRESS) in children: An EAACI position paper

Pediatric Allergy and Immunology, Volume 36, Issue 7, July 2025.
Abstract Background Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare but severe cutaneous adverse drug reaction encountered in both adults and children with a significant mortality rate. A number of guidelines or consensus reports have been published for optimal diagnosis and treatment of DRESS in adults, but none specifically ...
Semanur Kuyucu, Natalia Blanca‐Lopez, Jean‐Christoph Caubet, Luis Moral, Bernardo Sousa‐Pinto, Ozge Yılmaz Topal, Francesca Mori, Marina Atanaskovic Markovic, Eva Gomes   +8 more
wiley   +1 more source