Results 121 to 130 of about 608,679 (284)
Human herpesvirus-8 in northwestern China: epidemiology and characterization among blood donors
Virology Journal, 2010 BackgroundHuman herpes virus 8 (HHV-8) is the etiologic agent associated with development of classical, AIDS-related, iatrogenic, and endemic Kaposi's sarcoma (KS).
Xing Wang +9 more
semanticscholar +1 more source
Brain Pathology, EarlyView.HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie +9 more
wiley +1 more source
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]
, 2017 KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara +7 more
core +2 more sources
In vitro and in vivo human herpesvirus 8 infection of placenta.
PLoS ONE, 2008 Herpesvirus infection of placenta may be harmful in pregnancy leading to disorders in fetal growth, premature delivery, miscarriage, or major congenital abnormalities.
Mariantonietta Di Stefano +13 more
doaj +1 more source
Cytokine production by human herpesvirus 8-infected dendritic cells.
Journal of General Virology, 2009 We have shown previously that human herpesvirus 8 (HHV-8)-infected dendritic cells (DCs) undergo incomplete maturation and have a defective antigen-presenting function.
H. Hensler +3 more
semanticscholar +1 more source
Organoid Models to Study Human Infectious Diseases
Cell Proliferation, EarlyView.Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu +4 more
wiley +1 more source
Viral hijacking of cellular metabolism. [PDF]
, 2019 This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James +2 more
core
Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]
, 2018 Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li +9 more
core +3 more sources
Human Herpesvirus 8 Induces Polyfunctional B Lymphocytes That Drive Kaposi’s Sarcoma
mBio, 2014 Kaposi’s sarcoma (KS) is an unusual neoplasia wherein the tumor consists primarily of endothelial cells infected with human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) that are not fully transformed but are instead driven to excess ...
Emilee R. Knowlton +10 more
doaj +1 more source