Results 41 to 50 of about 456,074 (208)

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Machine Explanations and Human Understanding [PDF]

arXiv, 2022
Explanations are hypothesized to improve human understanding of machine learning models and achieve a variety of desirable outcomes, ranging from model debugging to enhancing human decision making. However, empirical studies have found mixed and even negative results.
arxiv  

HIV-negative disseminated Kaposi’s sarcoma in a Taiwanese patient

Kaohsiung Journal of Medical Sciences, 2011
Kaposi’s sarcoma is a common malignancy associated with HIV/AIDS. Herein, we describe the case of a 26-year-old man who presented with bilateral neck and inguinal lymphadenopathy, a massive tumor on the gum, and a nodule over the left eye.
Chiung-Tang Huang, Chao-Sung Chang, Hung-Chune Maa, Shih-Feng Cho, Ta-Chih Liu   +4 more
doaj   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, EarlyView.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Prevalence of human herpesvirus 8 infection in patients undergoing hemodialysis using nested-PCR

Journal of Acute Disease, 2019
Objective: To study the prevalence of HHV-8 infection in patients undergoing hemodialysis. Methods: In this study, blood samples of 89 patients undergoing hemodialysis were collected.
Somayeh Shokri, Shahab Mahmoudvand, Manoochehr Makvandi, Toran Shahani, Ali Samadi, Heshmatollah Shahbazian   +5 more
doaj   +1 more source

Skin microbiome engineering: Challenges and opportunities in skin diseases treatment

iMetaOmics, EarlyView.
The skin microbiome plays a crucial role in skin health, influencing barrier integrity, immune responses, and disease susceptibility. Various interventions can reshape the microbiome, broadly categorized into targeted and untargeted approaches. Targeted strategies, such as phage therapy, engineered bacteria, and phage lysins, selectively modulate ...
Yiang Lyu, Juntao Shen, You Che, Lei Dai
wiley   +1 more source

Reinforcement Learning on Human Decision Models for Uniquely Collaborative AI Teammates [PDF]

arXiv, 2021
In 2021 the Johns Hopkins University Applied Physics Laboratory held an internal challenge to develop artificially intelligent (AI) agents that could excel at the collaborative card game Hanabi. Agents were evaluated on their ability to play with human players whom the agents had never previously encountered.
arxiv  

Human herpesvirus 8 seropositivity among sexually active adults in Uganda.

PLoS ONE, 2011
IntroductionSexual transmission of human herpesvirus 8 (HHV8) has been implicated among homosexual men, but the evidence for sexual transmission among heterosexual individuals is controversial. We investigated the role of sexual transmission of HHV8 in a
Fatma M Shebl, Sheila C Dollard, Ruth M Pfeiffer, Benon Biryahwaho, Minal M Amin, Stella S Munuo, Wolfgang Hladik, Ruth Parsons, Barry I Graubard, Sam M Mbulaiteye   +9 more
doaj   +1 more source

Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient [PDF]

Anais Brasileiros de Dermatologia, 2016
The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides ...
Maria Carolina Prado Fleury Bariani, Luiz Fernando Fróes Fleury Júnior, Ana Maria Quinteiro Ribeiro, Siderley de Souza Carneiro, Tiago Arantes Pereira   +4 more
doaj   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source