Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona +6 more
doaj +1 more source
Case for diagnosis. Penile lesion in HIV-negative patient, [PDF]
We present the case of an HIV-negative man with asymptomatic penile erythematoviolaceous papules associated with similar slightly verrucous papules in the interdigital space of the right foot. A biopsy of the penile lesion confirmed Kaposi's sarcoma.
Mauro Cunha Ramos +3 more
doaj +1 more source
HHVs AND LYMPHOPROLIFERATIVE DISORDERS
Epstein-Barr virus (EBV) is a γ herpesvirus well recognized to be involved in the development of human B (Hodgkin and non Hodgkin lymphomas) and NK/T cell lymphomas, either in the general population or in the immunosuppressed individuals.
C Quadrelli +3 more
doaj +3 more sources
E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation
For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald +5 more
doaj +1 more source
The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N +12 more
core +2 more sources
High prevalence of antibodies to human herpesvirus 8 in relatives of patients with classic Kaposi's sarcoma from Sardinia [PDF]
A survey for antibodies to a recombinant small viral capsid antigen (sVCA) of human herpesvirus type 8 (HHV‐8) was conducted in Sardinia, one of the world's highest incidence areas for classic Kaposi's sarcoma (KS). Prevalence of antibodies to HHV‐8 sVCA
Angeloni, Antonio +11 more
core +1 more source
Harnessing Redox Disruption to Treat Human Herpesvirus 8 (HHV-8) Related Malignancies
Reprogrammed metabolism is regarded as a hallmark of cancer and offers a selective advantage to tumor cells during carcinogenesis. The redox equilibrium is necessary for growth, spread and the antioxidant pathways are boosted following Reactive Oxygen ...
Adélie Gothland +7 more
doaj +1 more source
Environmental factors influence the rate of human herpesvirus type 8 infection in a population with high incidence of classic Kaposi sarcoma [PDF]
High prevalence of human herpesvirus type 8 (HHV-8) infection has been reported on the island of Sardinia. Among emigrants from Sardinia, rates of HHV-8 infection are lower than they are in Sardinia and are similar to those observed in the local ...
Angeloni, Antonio +8 more
core +2 more sources
An alphaherpesvirus exploits antimicrobial beta-defensins to initiate respiratory tract infection [PDF]
beta-Defensins protect the respiratory tract against the myriad of microbial pathogens entering the airways with each breath. However, this potentially hostile environment is known to serve as a portal of entry for herpesviruses.
Boyen, Filip +8 more
core +2 more sources
Human herpesvirus 8 infection [PDF]
Human herpesvirus 8, also known as Kaposi sarcoma-associated herpesvirus, is etiologically associated with Kaposi sarcoma and other rare malignancies. Human herpesvirus 8 infection is common in certain areas of Africa and Italy, but occurs in only 0% to 15% of adult populations in North America and Europe. Reports of human herpesvirus 8 prevalence of 3%
openaire +2 more sources

