Angiosarcoma in HIV-negative patients is not associated with HHV-8 [PDF]
: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as ...
João Avancini +8 more
doaj +2 more sources
Molecular Detection of Human Herpesvirus-8 in Plasma and Peripheral Blood Mononuclear Cells of Patients with Cryptogenic Cirrhosis [PDF]
Background: Human herpesvirus-8 is the infectious etiology of endothelial origin in tumours with blood disorders. However, in some cirrhotic patients, no etiology can be identified, and such cases are known as cryptogenic cirrhosis. The aim of this study
Farah Bokharaei-Salim +5 more
doaj +1 more source
Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona +6 more
doaj +1 more source
Diagnostic Usefulness of Cell Block Samples in Fluid Overload-Associated Large B-Cell Lymphoma. [PDF]
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Okanishi H +14 more
europepmc +2 more sources
E3 Ubiquitin Ligases in Gammaherpesviruses and HIV: A Review of Virus Adaptation and Exploitation
For productive infection and replication to occur, viruses must control cellular machinery and counteract restriction factors and antiviral proteins.
Jessica Oswald +5 more
doaj +1 more source
Case for diagnosis. Penile lesion in HIV-negative patient, [PDF]
We present the case of an HIV-negative man with asymptomatic penile erythematoviolaceous papules associated with similar slightly verrucous papules in the interdigital space of the right foot. A biopsy of the penile lesion confirmed Kaposi's sarcoma.
Mauro Cunha Ramos +3 more
doaj +1 more source
HHVs AND LYMPHOPROLIFERATIVE DISORDERS
Epstein-Barr virus (EBV) is a γ herpesvirus well recognized to be involved in the development of human B (Hodgkin and non Hodgkin lymphomas) and NK/T cell lymphomas, either in the general population or in the immunosuppressed individuals.
C Quadrelli +3 more
doaj +3 more sources
Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA +5 more
core +1 more source
Heterogeneity of viral IL-6 expression in HHV-8-associated diseases. [PDF]
In order to characterize the expression of the viral interleukin-6 (vIL-6) homologue in various human herpesvirus 8 (HHV-8)-associated diseases, in situ hybridization and immunohistochemistry were applied to formalin-fixed specimens.
Cesarman, Ethel +9 more
core +1 more source
Harnessing Redox Disruption to Treat Human Herpesvirus 8 (HHV-8) Related Malignancies
Reprogrammed metabolism is regarded as a hallmark of cancer and offers a selective advantage to tumor cells during carcinogenesis. The redox equilibrium is necessary for growth, spread and the antioxidant pathways are boosted following Reactive Oxygen ...
Adélie Gothland +7 more
doaj +1 more source

