Results 41 to 50 of about 610,373 (247)

Human Herpesvirus 8: Current Issues [PDF]

open access: yesClinical Infectious Diseases, 2003
Although human herpesvirus 8 (HHV-8) is the etiologic agent of Kaposi sarcoma (KS), there are no formal guidelines for the clinical management of HHV-8 infection. In patients infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) is the best tool for the prevention of KS.
Michael J, Cannon   +2 more
openaire   +2 more sources

Clinical exuberance of classic Kaposi's sarcoma and response to radiotherapy [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
: Kaposi's sarcoma (KS) is a multicentric vascular neoplasm, with cutaneous and extracutaneous involvement. Different clinical and epidemiological variants have been identified.
Jeniffer Muñoz Trujillo   +5 more
doaj   +2 more sources

Oyster RNA-seq data support the development of Malacoherpesviridae genomics [PDF]

open access: yes, 2017
The family of double-stranded DNA (dsDNA) Malacoherpesviridae includes viruses able to infect marine mollusks and detrimental for worldwide aquaculture production. Due to fast-occurring mortality and a lack of permissive cell lines, the available data on
Rosani, Umberto, Venier, Paola
core   +2 more sources

Professional antigen presenting cells in human herpesvirus 8 infection

open access: yesFrontiers in Immunology, 2013
Professional antigen presenting cells (APC), i.e., dendritic cells, monocytes/macrophages, and B lymphocytes, are critically important in the recognition of an invading pathogen and presentation of antigens to the T cell-mediated arm of immunity.
Emilee R Knowlton   +7 more
doaj   +1 more source

An experimental evaluation of a loop versus a reference design for two-channel microarrays [PDF]

open access: yes, 2004
Motivation: Despite theoretical arguments that socalled "loop designs" of two-channel DNA microarray experiments are more efficient, biologists keep on using "reference designs".
C. P. Smith   +16 more
core   +2 more sources

HIV-associated lymphoma: A 5-year clinicopathologic study from India

open access: yesIndian Journal of Pathology and Microbiology, 2019
Context: Relative risk of non-Hodgkin lymphoma (NHL) in people living with HIV is 60–200 times that of normal population. This is the largest series from India on lymphomas arising in HIV-infected individuals including workup for Epstein–Barr virus (EBV)
Rajalakshmi Sampath   +4 more
doaj   +1 more source

Seroprevalence of Kaposi Sarcoma–associated Herpesvirus and Other Serologic Markers in the Brazilian Amazon

open access: yesEmerging Infectious Diseases, 2009
To determine the presence of Kaposi sarcoma–associated herpesvirus (KSHV) and other serologic markers, we tested serum specimens of 339 Amerindians, 181 rural non-Amerindians, and 1,133 urban blood donors (13 Amerindians) in the Brazilian Amazon.
Maria C. Nascimento   +10 more
doaj   +1 more source

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

open access: yes, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara   +7 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

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