Results 41 to 50 of about 84,279,697 (225)

A Toolbox for Herpesvirus miRNA Research: Construction of a Complete Set of KSHV miRNA Deletion Mutants

open access: yesViruses, 2016
Kaposi’s sarcoma-associated herpesvirus (KSHV) encodes 12 viral microRNAs (miRNAs) that are expressed during latency. Research into KSHV miRNA function has suffered from a lack of genetic systems to study viral miRNA mutations in the context of the viral
Vaibhav Jain   +10 more
doaj   +1 more source

Clinical exuberance of classic Kaposi's sarcoma and response to radiotherapy [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
: Kaposi's sarcoma (KS) is a multicentric vascular neoplasm, with cutaneous and extracutaneous involvement. Different clinical and epidemiological variants have been identified.
Jeniffer Muñoz Trujillo   +5 more
doaj   +2 more sources

Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]

open access: yes, 2011
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews   +14 more
core   +1 more source

Professional antigen presenting cells in human herpesvirus 8 infection

open access: yesFrontiers in Immunology, 2013
Professional antigen presenting cells (APC), i.e., dendritic cells, monocytes/macrophages, and B lymphocytes, are critically important in the recognition of an invading pathogen and presentation of antigens to the T cell-mediated arm of immunity.
Emilee R Knowlton   +7 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

HIV-associated lymphoma: A 5-year clinicopathologic study from India

open access: yesIndian Journal of Pathology and Microbiology, 2019
Context: Relative risk of non-Hodgkin lymphoma (NHL) in people living with HIV is 60–200 times that of normal population. This is the largest series from India on lymphomas arising in HIV-infected individuals including workup for Epstein–Barr virus (EBV)
Rajalakshmi Sampath   +4 more
doaj   +1 more source

Patterns of Human Herpesvirus-8 Oral Shedding among Diverse Cohorts of Human Herpesvirus-8 Seropositive Persons [PDF]

open access: yes, 2016
Human herpesvirus-8 (HHV-8), the etiologic agent of Kaposi sarcoma (KS), establishes lifelong latent infection with periodic lytic replication (“shedding”) at mucosal sites, especially the oropharynx.
Johnston, Christine   +9 more
core   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

open access: yesAdvanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen   +13 more
wiley   +1 more source

The Novel Viral Non‐Coding RNA LMP2A‐IT1 Promotes the Lytic Replication of EBV

open access: yesAdvanced Science, EarlyView.
Decades after its discovery, EBV's genome still harbours unannotated “dark matter”. LMP2A‐IT1, a novel EBV‐encoded transcript identified in this work, is strongly upregulated during lytic replication and promotes BZLF1 expression, likely through activation of inflammatory responses, thereby enhancing viral propagation in a self‐reinforcing positive ...
Zheng‐Zhou Lu   +15 more
wiley   +1 more source

Human Herpesvirus 8 (HHV8) Infection and Related Diseases in Italian Transplant Cohorts. [PDF]

open access: yes, 2013
Human Herpesvirus 8 (HHV8) Infection and Related Diseases in Italian Transplant ...
LUPPI, Mario   +38 more
core   +1 more source

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